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南非西北省非洲人心血管疾病危险因素的社会阶层流动:PURE研究

Social drift of cardiovascular disease risk factors in Africans from the North West Province of South Africa: the PURE study.

作者信息

Pisa P T, Behanan R, Vorster H H, Kruger A

机构信息

Centre of Excellence for Nutrition (CEN), North-West University, Potchefstroom, South Africa.

出版信息

Cardiovasc J Afr. 2012 Aug;23(7):371-8, e379-88. doi: 10.5830/CVJA-2012-018.

Abstract

OBJECTIVE

This study examined whether the association between socio-economic status (SES) and cardiovascular disease (CVD) risk factors in black South Africans from the North West Province had shifted from the more affluent groups with higher SES to the less affluent, lower SES groups over a period of nine years.

METHOD

Cross-sectional baseline data of 2 010 urban and rural subjects (35 years and older) participating in the Prospective Urban and Rural (PURE) study and collected in 2005 were analysed to examine the relationship of level of education, employment and urban or rural residence with dietary intakes and other CVD risk factors. These relationships were compared to those found nine years earlier in the Transition and Health during the Urbanisation of South Africans (THUSA) study conducted in the same area.

RESULTS

The results showed that urban women had higher body mass index (BMI), serum triglyceride and fasting glucose levels compared to rural women and that both urban men and women had higher blood pressures and followed a more Westernised diet. However, rural men and women had higher plasma fibrinogen levels. The more highly educated subjects (which included both urban and rural subjects) were younger than those with no or only primary school education. Few of the risk factors differed significantly between education groups, except that more highly educated men and women had lower BMIs, and women had lower blood pressure and triglyceride levels. These women also followed a more prudent diet than those with only primary school education. Employed men and women had higher BMIs, higher energy intakes but lower plasma fibrinogen levels, and employed women had lower triglyceride levels. No significant differences in total serum cholesterol values were observed.

CONCLUSION

These results suggest a drift of CVD risk factors from groups with higher SES to groups with a lower SES from 1996 to 2005, indicating that interventions to prevent CVD should also be targeted at Africans living in rural areas, those with low educational levels, and the unemployed.

摘要

目的

本研究调查了在九年时间里,西北省南非黑人的社会经济地位(SES)与心血管疾病(CVD)风险因素之间的关联是否已从SES较高的较富裕群体转移至SES较低的较贫困群体。

方法

分析了2005年收集的参与城乡前瞻性(PURE)研究的2010名城乡受试者(35岁及以上)的横断面基线数据,以研究教育水平、就业情况以及城乡居住状况与饮食摄入和其他CVD风险因素之间的关系。将这些关系与九年前在同一地区进行的南非人城市化过程中的转型与健康(THUSA)研究中发现的关系进行比较。

结果

结果显示,与农村女性相比,城市女性的体重指数(BMI)、血清甘油三酯和空腹血糖水平更高,并且城市男性和女性的血压更高,饮食更西化。然而,农村男性和女性的血浆纤维蛋白原水平更高。受教育程度较高的受试者(包括城乡受试者)比未受过教育或仅受过小学教育的受试者更年轻。除了受教育程度较高的男性和女性BMI较低,女性血压和甘油三酯水平较低外,各教育组之间的风险因素差异不大。这些女性的饮食也比仅受过小学教育的女性更为谨慎。就业的男性和女性BMI更高,能量摄入更高,但血浆纤维蛋白原水平更低,就业女性的甘油三酯水平更低。总血清胆固醇值未观察到显著差异。

结论

这些结果表明,从1996年到2005年,CVD风险因素已从SES较高的群体转移至SES较低的群体,这表明预防CVD的干预措施也应针对生活在农村地区、教育水平较低和失业的非洲人。

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