Wittig Jörn, Bredell Marius Gustav, Kruse Astrid, Haralambieva Eugenia, Grätz Klaus Wilhelm, Lübbers Heinz-Theo
Klinik für Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Zürich, Zürich, Switzerland.
Schweiz Monatsschr Zahnmed. 2012;122(7-8):619-27.
Tumorous lesions of the oral cavity are mostly of dental or local pathological origin. On occasion, they may have a distant origin outside the field of dentistry. Under certain circumstances, this can lead to serious consequences. Renal cell carcinomas are known for their frequent metastasis to the lungs, liver, bones, and brain. Metastases to the oral cavity are rare.
A 68-year-old woman with previously unknown renal cell carcinoma is presented. By biopsy of a suspicious lesion, an intraoral clear cell carcinoma was diagnosed. In the following tumor staging, a metastasizing clear cell renal cell carcinoma was identified as the focus and a systemic therapy was initiated.
This case report exemplarily shows the importance of timely histological verification of each new intraoral lesion. Under certain circumstances, a diagnosis of a surprising and potentially life-threatening condition may be made in time to initiate adequate treatment.
口腔肿瘤性病变大多起源于牙齿或局部病理因素。偶尔，它们可能起源于牙科领域之外的远处。在某些情况下，这可能导致严重后果。肾细胞癌以频繁转移至肺、肝、骨和脑而闻名。转移至口腔的情况罕见。
介绍一名68岁此前未知患有肾细胞癌的女性。通过对可疑病变进行活检，诊断为口腔内透明细胞癌。在接下来的肿瘤分期中，发现转移性透明细胞肾细胞癌为病灶并开始进行全身治疗。
本病例报告示例性地表明了及时对每一个新的口腔内病变进行组织学验证的重要性。在某些情况下，可能及时做出令人惊讶且可能危及生命的疾病诊断，从而启动适当的治疗。
