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工作压力与糖尿病和糖尿病前期有关:来自 MIPH 工业队列研究的横断面结果。

Work stress is associated with diabetes and prediabetes: cross-sectional results from the MIPH Industrial Cohort Studies.

机构信息

Mannheim Institute of Public Health, Social and Preventive Medicine, Mannheim Medical Faculty, Heidelberg University, Ludolf-Krehl-Strasse 7-11, 68167, Mannheim, Germany,

出版信息

Int J Behav Med. 2013 Dec;20(4):495-503. doi: 10.1007/s12529-012-9255-0.

Abstract

BACKGROUND

Diabetes is rapidly rising globally, and the relation of psychosocial stress in workplace to diabetes and prediabetes is not well investigated.

PURPOSE

The aim of the study was to examine the association of work stress with diabetes and prediabetes in a sample of German industrial workers.

METHOD

In this cross-sectional survey of an occupational cohort (n = 2,674, 77 % male), work stress was measured by the Effort-Reward Imbalance (ERI) Questionnaire. Diabetic status, i.e., diabetes and prediabetes, were diagnosed by glycated hemoglobin A1c criterion or fasting plasma glucose criterion supplemented by self-reports.

RESULTS

The overall prevalence rates of diabetes and prediabetes were 3.5 and 42.2 %, respectively. Using ordinal logistic regression with adjustment for potential confounding factors, high ERI at work was associated with diabetes-related ordinal variable (odds ratio [OR], 1.27; 95 % confidence interval [95 % CI], 1.02-1.58) and prediabetes-related ordinal variable (OR, 1.26; 95 % CI, 1.01-1.58) in men, whereas the associations in women were somewhat less pronounced and did not reach statistical significance.

CONCLUSION

The findings indicate that work stress in terms of ERI is associated with diabetes and prediabetes in German industrial male workers. If supported by prospective evidence, results point to a new approach towards primary prevention of diabetes.

摘要

背景

糖尿病在全球范围内迅速增加,工作场所的心理社会压力与糖尿病和糖尿病前期的关系尚未得到充分研究。

目的

本研究旨在调查德国工业工人样本中工作压力与糖尿病和糖尿病前期的关系。

方法

在这项职业队列的横断面研究中(n=2674,77%为男性),工作压力通过努力-回报失衡(ERI)问卷进行测量。糖尿病状态,即糖尿病和糖尿病前期,通过糖化血红蛋白 A1c 标准或空腹血糖标准结合自我报告进行诊断。

结果

糖尿病和糖尿病前期的总体患病率分别为 3.5%和 42.2%。使用有序逻辑回归模型调整潜在混杂因素后,工作中的高 ERI 与糖尿病相关的有序变量(比值比[OR],1.27;95%置信区间[95%CI],1.02-1.58)和糖尿病前期相关的有序变量(OR,1.26;95%CI,1.01-1.58)相关,而女性的相关性则稍弱,且未达到统计学意义。

结论

这些发现表明,ERI 方面的工作压力与德国工业男性工人的糖尿病和糖尿病前期有关。如果前瞻性证据支持这些结果,则表明这为糖尿病的一级预防提供了新的方法。

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