Department of Cardiology, Peking University Third Hospital and Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Int Arch Occup Environ Health. 2012 Feb;85(2):215-20. doi: 10.1007/s00420-011-0650-7. Epub 2011 May 31.
The studies focusing on effort-reward imbalance and diabetes mellitus (DM)/glycosylated hemoglobin (HbA1c) are rare. We sought to examine the association between job stress evaluated by effort-reward imbalance (ERI) model and HbA1c in a Chinese population.
We analyzed 680 subjects (465 men and 215 women) without DM or impaired glucose tolerance from the stress and health in Shenzhen workers (SHISO) study. Job stress was evaluated by effort-reward imbalance (ERI) model. HbA1c was measured by an automatic analyzer by means of high-performance liquid chromatography. The association between job stress and HbA1c was explored by variance analysis, partial correlations and multiple linear regression analysis.
For women, effort, and ERI were positively associated with HbA1c (r = 0.22, p = 0,003; r = 0.21, p = 0.006, respectively), in contrast, reward was negatively associated with HbA1c (r = -0.17, p = 0.021), after controlling age, BMI and physical exercise in the partial correlation analysis; the similar results were confirmed in the multiple linear regression. No significant correlations between job stress and HbA1c were found for men.
Effort and ERI are positively associated with HbA1c, and reward is inversely related to HbA1c among Chinese women. The association is not accounted for by age, BMI, and physical exercise. More efforts should be made to improve the job stress status of Chinese working women for the purpose of DM prevention.
关注工作努力-回报失衡与糖尿病（DM）/糖化血红蛋白（HbA1c）的研究较少。我们旨在研究中国人群中，工作努力-回报失衡（ERI）模型评估的职业压力与 HbA1c 之间的关系。
我们分析了来自深圳工作人群压力与健康（SHISO）研究的 680 名受试者（465 名男性和 215 名女性），这些受试者无糖尿病或糖耐量受损。职业压力通过努力-回报失衡（ERI）模型进行评估。HbA1c 通过高效液相色谱法自动分析仪进行测量。通过方差分析、偏相关分析和多元线性回归分析探索职业压力与 HbA1c 之间的关系。
对于女性，努力和 ERI 与 HbA1c 呈正相关（r = 0.22，p = 0.003；r = 0.21，p = 0.006），而回报与 HbA1c 呈负相关（r = -0.17，p = 0.021），在偏相关分析中控制年龄、BMI 和体育锻炼后；在多元线性回归中也得到了类似的结果。对于男性，职业压力与 HbA1c 之间没有显著相关性。
努力和 ERI 与 HbA1c 呈正相关，而回报与 HbA1c 呈负相关，这在中国女性中与年龄、BMI 和体育锻炼无关。应更加努力改善中国职业女性的工作压力状况，以预防糖尿病。
