Gazzeri Roberto, Galarza Marcelo, Alfier Alex
Department of Neurosurgery, San Giovanni Addolorata Hospital Rome, Italy.
Surg Technol Int. 2012 Dec;22:49-54.
Adequate hemostasis in cranial and spinal surgery is of paramount importance in a neurosurgeon's daily practice. Generalized ooze bleeding from the surgical wall cavities, coming from the dura mater or nervous tissue may be troublesome and may limit visualization in minimally invasive neurosurgery. Hemostatic matrix is a mixture of a flowable gelatin matrix (bovine or porcine) and a thrombin component mixed together. A total of 318 patients undergoing cranial, craniospinal, and spinal procedure with the use of gelatin hemostatic matrix (Floseal and Surgiflo) were enrolled in this clinical study. We compared the different hemostatic techniques using the gelatin hemostatic matrix, and investigated indications, time to bleeding control, and its efficacy and safety in neurosurgery.
在神经外科医生的日常实践中，颅脑和脊柱手术中充分止血至关重要。手术壁腔来自硬脑膜或神经组织的广泛性渗血可能会造成麻烦，并可能限制微创神经外科手术中的视野。止血基质是一种可流动的明胶基质（牛或猪）与凝血酶成分混合而成的混合物。本临床研究纳入了318例使用明胶止血基质（弗洛塞尔和 Surgiflo）进行颅脑、颅脊柱和脊柱手术的患者。我们比较了使用明胶止血基质的不同止血技术，并研究了其在神经外科手术中的适应证、出血控制时间及其有效性和安全性。
