Clément P, Paulet C
Département d'Anesthésie Réanimation, Hôpital Cochin, Paris.
Ann Urol (Paris). 1990;24(7):565-8.
The authors report on thirteen patients who developed a variety of symptoms after transurethral resection of the prostate; confusion, seizures, blurred vision with mydriasis, nausea and vomiting, bradycardia, and hypotension. This post-resection syndrome is caused by resorption of a large amount of the hypotonic solution used during the surgical procedure and containing 1.5% glycine. Postoperative sodium levels were assayed in all patients and consistently found to be low (105 to 124 mEq/l). Serum glycine was measured in three patients and the very high levels found suggest that absorption of glycine during transurethral resection of the prostate may contribute to the symptoms of encephalopathy.
作者报告了13例患者，他们在经尿道前列腺切除术后出现了多种症状，包括意识模糊、癫痫发作、瞳孔散大伴视力模糊、恶心呕吐、心动过缓和低血压。这种切除术后综合征是由于手术过程中使用的大量含1.5%甘氨酸的低渗溶液被吸收所致。对所有患者术后的钠水平进行了检测，结果一直显示偏低（105至124 mEq/l）。对3例患者测定了血清甘氨酸水平，发现其水平非常高，这表明经尿道前列腺切除术中甘氨酸的吸收可能导致脑病症状。
