Lardennois B, Clément T, Coulon J M, Brandt B
Service d'Urologie, CHRU Reims, Hôpital Robert-Debré.
Ann Urol (Paris). 1990;24(7):571-80.
The complexity of the mode of operation of the bladder and urinary sphincter has led to the development of a number of temporospatial physiologic models that divide the process of micturition into several stages in order to facilitate investigations. Ten years ago, the authors described a two-stage continence-micturition model intended to improve the accuracy of studies of urodynamic disorders and thus contribute to the development of more effective and more rational therapeutic solutions. A large number of diseases can affect the distal urinary tract and recent advances in neurophysiology [10] have made the selection of the appropriate therapy extremely complex. Consequently, the authors have developed a decision analysis system that simultaneously confronts diseases, urodynamic manifestations, risks for the patient, and the main therapeutic approaches available. In 1985, they increased the number of stages in their continence-micturition model from two the four. This four-stage model has provided satisfactory result when used with an abacus for modeling observed biologic phenomena. In addition to offering simulation exercises for teaching purposes, this abacus provides the means for studying the instantaneous urodynamic situation (correspondences between cycle time points, symptoms, and effects of treatments) and determining the effect of various medicosocial events on the course of the bladder and sphincter dysfunction. The authors hope this abacus will be an attractive aide to the understanding of the complex function of the distal urinary tract.
膀胱和尿道括约肌的运作模式十分复杂,这促使了一些时空生理模型的发展,这些模型将排尿过程划分为几个阶段,以便于开展研究。十年前,作者们描述了一种两阶段的控尿 - 排尿模型,旨在提高对尿动力学障碍研究的准确性,从而推动更有效、更合理治疗方案的开发。大量疾病会影响泌尿系统远端,而且神经生理学的最新进展[10]使得选择合适的治疗方法变得极为复杂。因此,作者们开发了一个决策分析系统,该系统能同时考量疾病、尿动力学表现、患者风险以及现有的主要治疗方法。1985年,他们将控尿 - 排尿模型的阶段数从两个增加到了四个。当与算盘一起用于模拟观察到的生物现象时,这个四阶段模型取得了令人满意的结果。除了用于教学目的的模拟练习外,这个算盘还提供了研究即时尿动力学情况(周期时间点、症状和治疗效果之间的对应关系)以及确定各种社会医学事件对膀胱和括约肌功能障碍病程影响的方法。作者们希望这个算盘将成为理解泌尿系统远端复杂功能的一个有吸引力的辅助工具。