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肝硬化患者的门静脉高压和静脉曲张

Portal hypertension and varices in patients with liver cirrhosis.

作者信息

Fullwood Danielle

机构信息

Institute of Liver Studies, King's College Hospital, London.

出版信息

Nurs Stand. 2012;26(48):52-7; quiz 58. doi: 10.7748/ns2012.08.26.48.52.c9230.

Abstract

Portal hypertension is a complication seen in patients with liver cirrhosis and is characterised by high pressure in the portal vein. As portal hypertension worsens, varices can form, leading to increased morbidity and mortality if these rupture. Bleeding can be prevented with pharmacological agents and endoscopic therapy; however, some patients will experience variceal haemorrhage. Medical and nursing management of acute variceal haemorrhage is key to a successful outcome, and after initial resuscitation, endoscopic therapy should be undertaken. Long-term management to prevent re-bleeding may involve surgery to implant shunts, which aim to reduce portal venous pressure. However, patients often require referral to specialist centres for transplant assessment.

摘要

门静脉高压是肝硬化患者中出现的一种并发症,其特征为门静脉压力升高。随着门静脉高压的加重,可形成静脉曲张,若这些静脉曲张破裂,会导致发病率和死亡率增加。使用药物和内镜治疗可预防出血;然而,一些患者仍会发生静脉曲张出血。急性静脉曲张出血的医疗和护理管理是取得成功结果的关键,在初始复苏后,应进行内镜治疗。预防再次出血的长期管理可能包括进行手术植入分流器,其目的是降低门静脉压力。然而,患者通常需要转诊至专科中心进行移植评估。

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