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口服抗酸剂对口服氟康唑药代动力学的影响。

Effect of oral antacid administration on the pharmacokinetics of oral fluconazole.

作者信息

Thorpe J E, Baker N, Bromet-Petit M

机构信息

Department of Clinical Research Pfizer Central Research, Sandwich, Kent United Kingdom.

出版信息

Antimicrob Agents Chemother. 1990 Oct;34(10):2032-3. doi: 10.1128/AAC.34.10.2032.

Abstract

Absorption and elimination of fluconazole after oral administration of a 100-mg capsule were unaffected by concomitant administration of an antacid containing aluminum and magnesium hydroxides.

摘要

口服100毫克胶囊后,氟康唑的吸收和消除不受同时服用含氢氧化铝和氢氧化镁抗酸剂的影响。

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