Castillo Jimeno J M, Santiago A M, Sebastián J L, Ruiz J L, Pérez Unzu A, Puras A, Marcotegui F
Servicio de Urología, Hospital Virgen del Camino, Pamplona, España.
Arch Esp Urol. 1990 Oct;43(8):819-28.
Sclerosant therapy for different pathological conditions (testicular hydrocele, pneumothorax) is a little known and scantily used procedure in the clinical setting. We have developed a surgical procedure in the dog that permits reproducing adult hydrocele. This experimental model is useful for morphometric assessment of the sclerosant effects of the commonly used agents (magnesium silicate hydrate, carbolic acid, ethanolamine oleate, hydroxytetracycline chlorhydrate and quinacrine chlorhydrate). Our results show that the degree of sclerosis achieved with quinacrine and hydrotetracycline is significantly superior to that obtained with other agents.
硬化剂疗法针对不同病理状况（睾丸鞘膜积液、气胸）在临床环境中是一种鲜为人知且使用较少的程序。我们已经在犬类身上开发出一种手术程序，可重现成年犬的鞘膜积液。该实验模型对于常用药剂（水合硅酸镁、石炭酸、油酸乙醇胺、盐酸羟四环素和盐酸阿的平）硬化剂效果的形态测量评估很有用。我们的结果表明，阿的平和氢四环素所达到的硬化程度明显优于其他药剂所获得的硬化程度。
