Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Gastroenterol Clin North Am. 2012 Sep;41(3):603-10. doi: 10.1016/j.gtc.2012.06.008. Epub 2012 Jul 6.
Circulating agents cause intestinal secretion or changes in motility with decreased intestinal transit time, resulting in secretory-type diarrhea. Secretory diarrhea as opposed to osmotic diarrhea is characterized by large-volume, watery stools, often more than 1 L per day; by persistence of diarrhea when patients fast; and by the fact that on analysis of stool-water, measured osmolarity is identical to that calculated from the electrolytes present. Although sodium plays the main role in water and electrolyte absorption, chloride is the major ion involved in secretion.
循环介质引起肠道分泌或运动改变，使肠道传输时间缩短，导致分泌性腹泻。与渗透性腹泻相反，分泌性腹泻的特征是大量水样便，每天通常超过 1 升；患者禁食时腹泻持续存在；以及粪便水分分析表明，实际测量的渗透压与根据存在的电解质计算出的渗透压相同。尽管钠在水和电解质吸收中起主要作用，但氯离子是分泌中涉及的主要离子。
