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外周钙化牙源性囊肿:一例报告及60年文献综述

Peripheral calcifying odontogenic cyst: a case report and comprehensive review of 60 years of literature.

作者信息

Sheng Sally, Tipton Nicholas, Chang Jennifer, Meng Hsiu-Wan, Tribble Gena D

机构信息

School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX, United States.

出版信息

Front Oral Health. 2023 Aug 4;4:1223943. doi: 10.3389/froh.2023.1223943. eCollection 2023.

Abstract

Peripheral Calcifying Odontogenic Cyst (PCOC) is the extraosseous form of calcifying odontogenic cyst that is limited to peripheral soft tissue without bony involvement. This case report presents a case of PCOC manifested as a progressive growth of gingival mass in a young male treated with excisional biopsy. Histological examination confirmed diagnosis of PCOC with presence of characteristic ghost cells and sporadic calcifications. No recurrence of the lesion and no complication were noted at three-year follow-up. Review of available literature on PCOC noted a predilection of occurrence in the mandible (61%) and in the anterior area of the jaws (58%). Mean age of patients was 41.7 ± SD25.43 (7-83) and 95% CI [33.6, 49.8] yrs. Mean size of the lesions was 1.38 ± SD1.1 (0.5-4.3) and 95% CI [0.93, 1.83] cm. Gender distribution was noted to be 51.3% male and 48.7% female.

摘要

外周钙化牙源性囊肿(PCOC)是牙源性钙化囊肿的骨外形式,局限于外周软组织,不累及骨组织。本病例报告介绍了一例PCOC,表现为一名年轻男性牙龈肿物进行性生长,采用切除活检进行治疗。组织学检查确诊为PCOC,可见特征性的影细胞和散在钙化。三年随访期间未发现病变复发及并发症。回顾关于PCOC的现有文献发现,该疾病好发于下颌骨(61%)及颌骨前部区域(58%)。患者的平均年龄为41.7±标准差25.43(7 - 83)岁,95%置信区间为[33.6, 49.8]岁。病变的平均大小为1.38±标准差1.1(0.5 - 4.3)厘米,95%置信区间为[0.93, 1.83]厘米。性别分布为男性占51.3%,女性占48.7%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bd3/10436745/af6e0b13d47b/froh-04-1223943-g001.jpg

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