Markovic Jovan N, Kim Charles Y, Lidsky Michael E, Shortell Cynthia K
Duke University School of Medicine, Durham, NC, USA.
Perspect Vasc Surg Endovasc Ther. 2012 Jun;24(2):70-9. doi: 10.1177/1531003512457205. Epub 2012 Aug 22.
In this study, the authors present an analysis of the outcomes of 105 low-flow vascular malformation patients treated over a 6-year period and report specific lesion characteristics that correlate with those vascular malformations that will benefit from sodium tetradecyl sulfate foam sclerotherapy (STS FS) versus surgical resection as well as morphological characteristics of vascular malformations that are associated with a poor response to FS treatment. Improvement in symptoms was documented in 92.9% of patients treated with STS FS. There were no complications. Low-flow vascular malformations that were morphologically characterized by microcystic, septated vessels did not respond to FS, and these vascular malformations are best treated with surgical resection. Primary surgical resection is also the treatment of choice for localized, microcystic, and superficial low-flow vascular malformations. Symptomatic, diffuse, extensive, macrocystic malformations that involve multiple tissue planes and vital structures are best treated with FS.
在本研究中，作者对6年期间治疗的105例低流量血管畸形患者的治疗结果进行了分析，并报告了与那些将从十四烷基硫酸钠泡沫硬化疗法（STS FS）与手术切除中获益的血管畸形相关的特定病变特征，以及与FS治疗反应不佳相关的血管畸形的形态学特征。接受STS FS治疗的患者中有92.9%记录到症状改善。无并发症发生。形态学上以微囊状、有分隔的血管为特征的低流量血管畸形对FS无反应，这些血管畸形最好采用手术切除治疗。原发性手术切除也是局限性、微囊状和浅表性低流量血管畸形的首选治疗方法。有症状的、弥漫性、广泛性、累及多个组织平面和重要结构的大囊状畸形最好采用FS治疗。
