Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Dermatol Surg. 2010 Mar;36(3):340-6. doi: 10.1111/j.1524-4725.2009.01440.x. Epub 2010 Jan 19.
Vascular malformations have devastating cosmetic effects in addition to being associated with pain and bleeding. Sclerotherapy has been successfully used in treating complicated hemangiomas and vascular malformations.
To assess the efficacy of sclerotherapy with 3% sodium tetradecyl sulphate (STS) in venous and lymphatic malformations.
We performed sclerotherapy with 3% STS in 13 patients with venous malformations and microcystic lymphatic malformation, all low-flow malformations and with extent predominantly to the subcutis, confirmed using Doppler ultrasound. Lesions were located on the face, lower lip, flanks, buttocks, and extremities. Patients presented for cosmetic reasons, pain, or bleeding. Sclerotherapy was undertaken as an office procedure without any radiological guidance and therapy repeated every 3 weeks. Therapeutic efficacy was assessed subjectively clinically and photographically.
The lesions regressed by 90% to 100% in 11 cases after a mean of four injections, with no improvement in two cases (one each of venous malformation and lymphatic malformation). Complications included cutaneous blister formation, erosions, and crusting at injection site in seven cases and atrophic scarring in four patients.
Sclerotherapy with 3% STS is a simple, safe, and effective modality for venous malformations and can be undertaken as an office procedure in lesions limited to the subcutis.
血管畸形除了与疼痛和出血有关外，还会造成严重的美容影响。硬化疗法已成功用于治疗复杂的血管瘤和血管畸形。
评估 3%十四烷基硫酸钠（STS）硬化疗法治疗静脉和淋巴管畸形的疗效。
我们对 13 例静脉畸形和微囊性淋巴管畸形患者进行了 3% STS 硬化疗法，所有病变均为低流量畸形，主要累及皮下组织，通过多普勒超声确认。病变位于面部、下唇、侧腹、臀部和四肢。患者因美容、疼痛或出血就诊。硬化疗法作为门诊程序进行，无需任何放射学指导，每 3 周重复治疗。通过临床和摄影评估治疗效果。
11 例患者在平均接受 4 次注射后，病变消退 90%至 100%，2 例（静脉畸形和淋巴管畸形各 1 例）无改善。并发症包括 7 例注射部位皮肤水疱形成、糜烂和结痂，4 例患者出现萎缩性瘢痕。
3% STS 硬化疗法是一种治疗静脉畸形的简单、安全、有效的方法，可以在局限于皮下组织的病变中作为门诊程序进行。
