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The role of secondary surgery in recurrent ovarian cancer.二次手术在复发性卵巢癌中的作用。
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Critical evaluation of secondary cytoreduction in recurrent ovarian cancer.复发性卵巢癌二次肿瘤细胞减灭术的批判性评估
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本文引用的文献

1
Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial.早期与延迟治疗复发性卵巢癌（MRC OV05/EORTC 55955）：一项随机试验。
Lancet. 2010 Oct 2;376(9747):1155-63. doi: 10.1016/S0140-6736(10)61268-8.
2
Cytoreductive surgery plus chemotherapy versus chemotherapy alone for recurrent epithelial ovarian cancer.减瘤手术联合化疗与单纯化疗治疗复发性上皮性卵巢癌的比较
Cochrane Database Syst Rev. 2010 Jun 16;2010(6):CD007822. doi: 10.1002/14651858.CD007822.pub2.
3
Hyperthermic intra-peritoneal chemotherapy using oxaliplatin as consolidation therapy for advanced epithelial ovarian carcinoma. Results of a phase II prospective multicentre trial. CHIPOVAC study.腹腔内热灌注化疗联合奥沙利铂巩固治疗晚期上皮性卵巢癌的前瞻性Ⅱ期多中心临床研究。CHIPOVAC 研究。
Eur J Surg Oncol. 2010 Jun;36(6):589-93. doi: 10.1016/j.ejso.2010.04.005. Epub 2010 May 13.
4
Surveillance for the detection of recurrent ovarian cancer: survival impact or lead-time bias?卵巢癌复发的监测：生存影响还是领先时间偏倚？
Gynecol Oncol. 2010 May;117(2):336-40. doi: 10.1016/j.ygyno.2010.01.014. Epub 2010 Feb 12.
5
Should the treatment of peritoneal carcinomatosis by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy still be regarded as a highly morbid procedure?: a systematic review of morbidity and mortality.减瘤手术联合腹腔内热灌注化疗治疗腹膜癌病是否仍应被视为高风险手术？：一项关于发病率和死亡率的系统评价
Ann Surg. 2009 Jun;249(6):900-7. doi: 10.1097/SLA.0b013e3181a45d86.
6
Surgery for recurrent ovarian cancer: role of peritoneal carcinomatosis: exploratory analysis of the DESKTOP I Trial about risk factors, surgical implications, and prognostic value of peritoneal carcinomatosis.复发性卵巢癌的手术治疗：腹膜癌的作用：关于腹膜癌危险因素、手术意义及预后价值的DESKTOP I试验探索性分析
Ann Surg Oncol. 2009 May;16(5):1324-30. doi: 10.1245/s10434-009-0357-0. Epub 2009 Feb 19.
7
Cytoreductive surgery for recurrent ovarian cancer: a meta-analysis.复发性卵巢癌的细胞减灭术：一项荟萃分析
Gynecol Oncol. 2009 Jan;112(1):265-74. doi: 10.1016/j.ygyno.2008.08.033. Epub 2008 Oct 19.
8
Predictive value of PET-CT imaging versus AGO-scoring in patients planned for cytoreductive surgery in recurrent ovarian cancer.正电子发射断层显像（PET-CT）成像与AGO评分对计划进行复发性卵巢癌肿瘤细胞减灭术患者的预测价值
Eur J Obstet Gynecol Reprod Biol. 2008 Oct;140(2):263-8. doi: 10.1016/j.ejogrb.2008.05.006. Epub 2008 Jul 9.
9
Secondary cytoreductive surgery in patients with platinum-sensitive recurrent ovarian cancer.铂敏感复发性卵巢癌患者的二次肿瘤细胞减灭术
Ann Surg Oncol. 2007 Mar;14(3):1136-42. doi: 10.1245/s10434-006-9273-8. Epub 2006 Dec 31.
10
A systematic review on the efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for diffuse malignancy peritoneal mesothelioma.一项关于减瘤手术联合围手术期腹腔内化疗治疗弥漫性恶性腹膜间皮瘤疗效的系统评价。
Ann Oncol. 2007 May;18(5):827-34. doi: 10.1093/annonc/mdl428. Epub 2006 Nov 27.

二次手术在复发性卵巢癌中的作用。

The role of secondary surgery in recurrent ovarian cancer.

作者信息

Lorusso D, Mancini M, Di Rocco R, Fontanelli R, Raspagliesi F

机构信息

Fondazione IRCCS Istituto Nazionale Tumori, Via Venezian 1, 20133 Milan, Italy.

出版信息

Int J Surg Oncol. 2012;2012:613980. doi: 10.1155/2012/613980. Epub 2012 Aug 5.

DOI:10.1155/2012/613980
PMID:22919475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3420128/
Abstract

Despite optimal treatment (complete cytoreduction and adjuvant chemotherapy), 5-year survival for advanced ovarian cancer is approximately 30% and most patients succumb to their disease. Cytoreductive surgery is accepted as a major treatment of primary ovarian cancer but its role in recurrent disease is controversial and remains a field of discussion mainly owing to missing data from prospective randomized trials. A critical review of literature evidence on secondary surgery in recurrent ovarian cancer will be described.

摘要

尽管进行了最佳治疗（完全细胞减灭术和辅助化疗），晚期卵巢癌的5年生存率约为30%，大多数患者最终死于该疾病。细胞减灭术被公认为原发性卵巢癌的主要治疗方法，但其在复发性疾病中的作用存在争议，仍是一个主要因前瞻性随机试验数据缺失而有待讨论的领域。本文将对复发性卵巢癌二次手术的文献证据进行批判性综述。