Lorusso D, Mancini M, Di Rocco R, Fontanelli R, Raspagliesi F
Fondazione IRCCS Istituto Nazionale Tumori, Via Venezian 1, 20133 Milan, Italy.
Int J Surg Oncol. 2012;2012:613980. doi: 10.1155/2012/613980. Epub 2012 Aug 5.
Despite optimal treatment (complete cytoreduction and adjuvant chemotherapy), 5-year survival for advanced ovarian cancer is approximately 30% and most patients succumb to their disease. Cytoreductive surgery is accepted as a major treatment of primary ovarian cancer but its role in recurrent disease is controversial and remains a field of discussion mainly owing to missing data from prospective randomized trials. A critical review of literature evidence on secondary surgery in recurrent ovarian cancer will be described.
尽管进行了最佳治疗(完全细胞减灭术和辅助化疗),晚期卵巢癌的5年生存率约为30%,大多数患者最终死于该疾病。细胞减灭术被公认为原发性卵巢癌的主要治疗方法,但其在复发性疾病中的作用存在争议,仍是一个主要因前瞻性随机试验数据缺失而有待讨论的领域。本文将对复发性卵巢癌二次手术的文献证据进行批判性综述。