Isaev I M
Biull Eksp Biol Med. 1990 Aug;110(8):216-7.
Neurohistochemical methods were applied to study adrenergic and cholinergic nervous structures of pulmonary tissue in 30 patients aged 14-82 who had died of burn disease at various stages of its progress (shock, toxemia, septic toxemia). Autopsies performed within 4 hours after the patients' death evidenced mediators depletion in perivascular and peribronchial plexuses as well as intensive luminescence of nervous fibers considered as compensatory adaptation. There was cholinesterase hypoactivity in cholinergic plexuses. It is established that the failure of adaptive-trophic sympathetic regulation of pulmonary tissues including relevant vessels and bronchi results in diminution of pulmonary compensatory and adaptive potential. This should be allowed for in the treatment of burn disease complications.
应用神经组织化学方法，对30例年龄在14 - 82岁之间、死于烧伤疾病不同进展阶段（休克、毒血症、败血性毒血症）的患者的肺组织中的肾上腺素能和胆碱能神经结构进行了研究。在患者死亡后4小时内进行的尸检表明，血管周围和支气管周围神经丛中的介质耗竭，以及被视为代偿性适应的神经纤维的强烈荧光。胆碱能神经丛中存在胆碱酯酶活性降低的情况。已证实，包括相关血管和支气管在内的肺组织的适应性营养交感神经调节功能衰竭，会导致肺代偿和适应潜能降低。在治疗烧伤疾病并发症时应考虑到这一点。
