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慢性尿毒症中自主神经功能障碍的年龄依赖性发生情况。

Age-dependent occurrence of autonomic dysfunction in chronic uraemia.

作者信息

Vita G, Savica V, Marabello L, Puglisi R M, Serra S, Musolino R, Bellinghieri G, Messina C

机构信息

Chair of Experimental Nephrology, University of Messina, Italy.

出版信息

Funct Neurol. 1987 Oct-Dec;2(4):583-8.

PMID:3443385
Abstract

A battery of cardiovascular reflex tests were performed in twenty patients with chronic renal failure on intermittent haemodialysis. Using age-adjusted confidence limits, old-aged uraemics showed more extensive parasympathetic and sympathetic dysfunction than middle-aged patients. The results suggest that autonomic nervous system in the elderly is more susceptible to uraemic toxins than in the middle age. This should lead to better preventive and therapeutic strategies in older uraemics.

摘要

对20例接受间歇性血液透析的慢性肾衰竭患者进行了一系列心血管反射测试。采用年龄校正的置信区间,老年尿毒症患者比中年患者表现出更广泛的副交感神经和交感神经功能障碍。结果表明,老年人的自主神经系统比中年人更容易受到尿毒症毒素的影响。这应该会为老年尿毒症患者带来更好的预防和治疗策略。

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