Chusri Sarunyou, Sritrairatchai Somporn, Hortiwahul Thanaporn, Charoenmak Boonsri, Silpapojakul Khachomsakdi
Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
J Med Assoc Thai. 2012 Jul;95(7):874-7.
To assess epidemiology and risk factors for leptospirosis infection among the rafting participants in southern Thailand.
Prospective observation of the patients who participated in rafting in southern Thailand was conducted between January and December 2010. Demographic, clinical data as well as potential risk factors were collected Indirect immunofluorescent antibody test (IFAT) for specific leptospirosis IgG detection were examined immediately after rafting and two to three weeks after first samples. Microagglutination Test (MAT) was performed to confirm diagnosis in cases with seroconversion.
One hundred fifty eight rafting participants enrolled to the present study of which 150 complied with the protocol and were analyzed Eleven patients had serological evidence of leptospirosis infection accounting for 7.3% while only three patients were symptomatic. Various serovars are responsible for infection while serovar Icterohemorrhagiae is most common. Persistence of abrasion wound/laceration wound were likely to be risk factors for infection with p < 0.05.
The laboratory findings in the present study demonstrated that leptospirosis was associated with rafting and a contaminated environment.
评估泰国南部漂流参与者中钩端螺旋体感染的流行病学及危险因素。
2010年1月至12月对参与泰国南部漂流的患者进行前瞻性观察。收集人口统计学、临床数据以及潜在危险因素。漂流结束后立即及首次采样后两到三周检测特异性钩端螺旋体IgG的间接免疫荧光抗体试验（IFAT）。对血清转化的病例进行显微镜凝集试验（MAT）以确诊。
158名漂流参与者纳入本研究，其中150名符合方案并进行分析。11名患者有钩端螺旋体感染的血清学证据，占7.3%，而只有3名患者有症状。多种血清型导致感染，其中出血性黄疸型血清型最为常见。擦伤伤口/撕裂伤持续存在可能是感染的危险因素，p<0.05。
本研究的实验室结果表明，钩端螺旋体病与漂流及受污染环境有关。
