IBB CNR, Napoli, Via Pansini 5, 80131 Naples, Italy.
Clin Imaging. 2012 Sep-Oct;36(5):559-67. doi: 10.1016/j.clinimag.2012.01.015. Epub 2012 Jun 8.
To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptake<liver) and benign pathologies, and between ce-MDCT Pattern 1 (splenomegaly without focal lesions) and Pattern 2 (focal hypodense lesion) as well as PET/CT Pattern 1 (diffuse uptake ≥ liver) and Pattern 2 (focal increased uptake) and malignant diseases. No significant association between benign or malignant diseases and spleen volumes and maximum standardized uptake value (SUV(max)) as well as lesion characteristics was observed. The metabolic data do not improve the performance of morphological patterns.
为了评估体层摄影特征在鉴别脾脏良恶性疾病中的作用，回顾性选择了 54 例经细胞学和组织学检查以及增强多排螺旋 CT（ce-MDCT）和/或正电子发射断层扫描/计算机断层扫描（PET/CT）检查的患者。ce-MDCT 模式 3（局灶性高密度病变）和模式 4（梗死/囊肿）以及 PET/CT 模式 3（局灶性光稀疏/弥漫摄取<肝）与良性病变之间，以及 ce-MDCT 模式 1（脾肿大无局灶性病变）和模式 2（局灶性低密病变）以及 PET/CT 模式 1（弥漫摄取≥肝）和模式 2（局灶性摄取增加）与恶性病变之间存在显著相关性。良性或恶性疾病与脾脏体积和最大标准化摄取值（SUV(max)）以及病变特征之间无显著相关性。代谢数据并未改善形态学模式的性能。
