Cao Fang, Qian Wei, Ma Yanqing, Wu Yinbo, Zhong Jianguo
Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou medical College, Hangzhou, Zhejiang, China.
Department of Radiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Clin Imaging. 2018 May-Jun;49:58-64. doi: 10.1016/j.clinimag.2017.10.020. Epub 2017 Nov 10.
To assess the value of imaging features for differentiating malignant from benign focal splenic lesions, 79 pathologically proved cases with contrast-enhanced CT or MRI were retrospectively studied. The morphological characteristics were assessed and the enhancement patterns were classified into five categories. After multivariate logistic analysis, the lesion margin and enhancement patterns were significantly different between benign and malignant lesions. The combination of ill-defined margin and hypovascular enhancement for suggesting malignant lesions had a good specificity (94.9%) and accuracy (89.9%). Morphological and enhancement characteristics on CT/MRI may be valuable in differentiating malignant from benign focal splenic lesions.
为评估影像学特征在鉴别脾脏局灶性病变良恶性方面的价值，我们对79例经病理证实的行增强CT或MRI检查的病例进行了回顾性研究。评估了形态学特征，并将强化模式分为五类。经过多因素逻辑分析，良性和恶性病变之间的病变边缘和强化模式存在显著差异。边界不清和乏血供强化相结合提示恶性病变具有良好的特异性（94.9%）和准确性（89.9%）。CT/MRI上的形态学和强化特征在鉴别脾脏局灶性病变良恶性方面可能具有重要价值。
