Department of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania.
Semin Thorac Cardiovasc Surg. 2012 Summer;24(2):115-22. doi: 10.1053/j.semtcvs.2012.06.003.
Myasthenia gravis (MG) is a heterogeneous disorder with a fluctuating, clinical, pathologic, and immunobiological picture. Today, it is believed that effective treatment of MG must include both immunosuppression and surgery. Thymectomy is recommended by neurologists for patients with nontumoral MG as an option to increase the probability of remission or improvement. Currently, thoracoscopic thymectomy is considered a good alternative to the standard open approach because of its higher rate of acceptance, low morbidity, and high efficacy, as measured by complete stable remission rates. We present a review of the experience of unilateral extended thoracoscopic thymectomy for nontumoral MG, a technique that could became a new standard in the complex management of MG treatment.
重症肌无力(MG)是一种异质性疾病,具有波动性的临床、病理和免疫生物学特征。如今,人们认为,MG 的有效治疗必须包括免疫抑制和手术。胸腺瘤切除术被神经科医生推荐用于非肿瘤性 MG 患者,作为增加缓解或改善概率的一种选择。目前,由于其更高的接受率、低发病率和高疗效(以完全稳定缓解率衡量),胸腔镜胸腺切除术被认为是标准开胸手术的一种较好替代方法。我们回顾了单侧扩大胸腔镜胸腺切除术治疗非肿瘤性 MG 的经验,该技术可能成为 MG 治疗复杂管理中的新标准。