Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Ultrasound Med Biol. 2012 Oct;38(10):1778-83. doi: 10.1016/j.ultrasmedbio.2012.05.016. Epub 2012 Aug 21.
This study was aimed to quantify the underestimation of cardiac Doppler measurements and to explore a method for correction. A dual pulse wave (PW)/Doppler tissue imaging (DTI) mode echocardiographic technique was used in the in vitro and in vivo studies. In the in vitro experiment, we have demonstrated how cardiac valvular motion might interfere with blood velocity estimation using conventional Doppler. When examining the participants, we observed that adding valvular annulus velocity to determine the relative velocity between blood and valvular annulus would result in an increment of 9.3 ± 1.3 cm/s and 6.3 ± 0.9 cm/s for aortic and pulmonary blood flow, 12.8 ± 1.9 cm/s and 8.9 ± 1.4 cm/s for mitral E and A wave, 12.9 ± 1.8 cm/s and 10.2 ± 2.4 cm/s for tricuspid E and A wave. The underestimations of the Doppler measurements markedly influence the hemodynamic parameters commonly used in the clinical practices and researches. This study provides a quantitative method for the correction and would make the Doppler measurement accurate.
本研究旨在量化心脏多普勒测量的低估，并探索一种校正方法。在体外和体内研究中使用了双脉冲波（PW）/多普勒组织成像（DTI）模式超声心动图技术。在体外实验中，我们展示了心脏瓣膜运动如何通过常规多普勒干扰血流速度估计。在检查参与者时，我们观察到，通过添加瓣环速度来确定血液与瓣环之间的相对速度，会导致主动脉和肺动脉血流分别增加 9.3 ± 1.3 cm/s 和 6.3 ± 0.9 cm/s，二尖瓣 E 和 A 波分别增加 12.8 ± 1.9 cm/s 和 8.9 ± 1.4 cm/s，三尖瓣 E 和 A 波分别增加 12.9 ± 1.8 cm/s 和 10.2 ± 2.4 cm/s。多普勒测量的低估显著影响临床实践和研究中常用的血流动力学参数。本研究提供了一种定量校正方法，可使多普勒测量更加准确。
