University of Texas Southwestern Medical Center, Dallas, Texas 75390-8550, USA.
Am J Cardiol. 2012 Sep 15;110(6 Suppl):3S-8S. doi: 10.1016/j.amjcard.2012.06.010.
Our ability to evaluate the right ventricle (RV) in pulmonary hypertension has traditionally been quite limited: the RV's complex anatomy is not adequately represented by 2-dimensional imaging, and our understanding of what is an adaptive and maladaptive RV response is incomplete. However, measures of RV function appear to be a strong predictor of survival in pulmonary hypertension. This is, therefore, a promising area for future study. To more fully understand the challenges and opportunities in this area, this article provides a review of RV embryology and anatomy, current assessment of the RV function, animal models of RV function, RV-pulmonary artery coupling, and how translating lessons from studies of the left ventricle may increase our knowledge of the RV.
我们评估肺动脉高压患者右心室（RV）的能力一直受到很大限制：二维成像无法充分显示 RV 复杂的解剖结构，而我们对适应性和适应性不良 RV 反应的理解也不完整。然而，RV 功能的测量似乎是肺动脉高压患者生存的有力预测指标。因此，这是一个有前途的研究领域。为了更全面地了解这一领域的挑战和机遇，本文回顾了 RV 的胚胎学和解剖学、RV 功能的当前评估、RV 功能的动物模型、RV-肺动脉耦联以及从左心室研究中吸取的经验教训如何增加我们对 RV 的了解。
