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Receptor interactions of imidazolines. III. Structure-activity relationships governing alpha adrenergic receptor occupation and receptor activation for mono- and dimethoxy-substituted tolazoline derivatives in rat aorta.

作者信息

Ruffolo R R, Dillard R D, Waddell J E, Yaden E L

出版信息

J Pharmacol Exp Ther. 1979 Dec;211(3):733-8.

PMID:229213
Abstract
摘要

相似文献

1
Receptor interactions of imidazolines. III. Structure-activity relationships governing alpha adrenergic receptor occupation and receptor activation for mono- and dimethoxy-substituted tolazoline derivatives in rat aorta.咪唑啉的受体相互作用。III. 大鼠主动脉中一甲氧基和二甲氧基取代的妥拉唑啉衍生物对α肾上腺素能受体占据和受体激活的构效关系。
J Pharmacol Exp Ther. 1979 Dec;211(3):733-8.
2
Receptor interactions of imidazolines. II. Affinities and efficacies of hydroxy-substituted tolazoline derivatives in rat aorta.咪唑啉的受体相互作用。II. 羟基取代妥拉唑啉衍生物在大鼠主动脉中的亲和力和效能。
J Pharmacol Exp Ther. 1979 Oct;211(1):74-9.
3
Receptor interactions of imidazolines. VII. Peripherally mediated pressor and centrally mediated depressor effects of clonidine and a series of mono- and dimethoxy-substituted tolazoline derivatives.咪唑啉的受体相互作用。VII. 可乐定及一系列单甲氧基和二甲氧基取代的妥拉唑啉衍生物的外周介导升压作用和中枢介导降压作用
J Pharmacol Exp Ther. 1981 Jul;218(1):154-60.
4
Receptor interactions of imidazolines. I. Affinity and efficacy for alpha adrenergic receptors in rat aorta.咪唑啉的受体相互作用。I. 对大鼠主动脉α肾上腺素能受体的亲和力和效能。
J Pharmacol Exp Ther. 1979 Jun;209(3):429-36.
5
Receptor interactions of imidazolines. IV. Structural requirements for alpha adrenergic receptor occupation and receptor activation by clonidine and a series of structural analogs in rat aorta.咪唑啉的受体相互作用。IV. 可乐定及一系列结构类似物在大鼠主动脉中占据α肾上腺素能受体和激活受体的结构要求。
J Pharmacol Exp Ther. 1980 May;213(2):267-72.
6
Receptor interactrions of imidazolines. VI. Significance of carbon bridge separating phenyl and imidazoline rings of tolazoline-like alpha adrenergic imidazolines.咪唑啉的受体相互作用。VI. 托拉唑啉样α肾上腺素能咪唑啉中分隔苯基和咪唑啉环的碳桥的意义。
J Pharmacol Exp Ther. 1980 Sep;214(3):535-40.
7
Interactions of dimethoxy-substituted tolazoline derivatives with alpha 1- and alpha 2-adrenoreceptors in vitro.二甲基氧基取代的妥拉唑啉衍生物在体外与α1和α2肾上腺素能受体的相互作用。
J Auton Pharmacol. 1985 Mar;5(1):71-9. doi: 10.1111/j.1474-8673.1985.tb00567.x.
8
Alpha-1 adrenergic coupling events induced by full and partial agonists in rabbit aorta.兔主动脉中完全激动剂和部分激动剂诱导的α-1肾上腺素能偶联事件
J Pharmacol Exp Ther. 1987 May;241(2):458-64.
9
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.一系列二甲氧基取代的妥拉唑啉衍生物在去大脑大鼠心血管系统中α-1和α-2肾上腺素能受体介导作用的评估。
J Pharmacol Exp Ther. 1985 Jan;232(1):94-9.
10
Receptor interactions of imidazolines. V. clonidine differentiates postsynaptic alpha adrenergic receptor subtypes in tissues from the rat.咪唑啉的受体相互作用。V.可乐定对大鼠组织中突触后α肾上腺素能受体亚型的区分
J Pharmacol Exp Ther. 1980 Jun;213(3):557-61.

引用本文的文献

1
Receptor interactions of imidazolines: alpha-adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists.咪唑啉的受体相互作用:通过咪唑啉激动剂的相对效价、亲和力和效能区分大鼠和兔主动脉的α-肾上腺素能受体
Br J Pharmacol. 1982 Sep;77(1):169-76. doi: 10.1111/j.1476-5381.1982.tb09283.x.
2
Interaction of enantiomers of hydroxy tolazoline with adrenoceptors.羟基妥拉唑啉对映体与肾上腺素能受体的相互作用。
Naunyn Schmiedebergs Arch Pharmacol. 1987 Apr;335(4):391-6. doi: 10.1007/BF00165553.