银杏叶对实验性快速上颌扩张模型的影响：一项组织形态计量学研究。
Effects of Ginkgo biloba on experimental rapid maxillary expansion model: a histomorphometric study.
机构信息
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Izmir Katip Celebi University, Izmir, Turkey.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Dec;114(6):712-8. doi: 10.1016/j.oooo.2012.03.007. Epub 2012 Aug 24.
OBJECTIVE
We aimed to investigate the effect of systemic Ginkgo biloba in rapid maxillary expansion (RME).
STUDY DESIGN
We randomly divided 24 rats into 3 groups: expansion only (EO), expansion plus Ginkgo biloba (GB), and no expansion (NE). Expansion appliances were affixed to the maxillary incisors. After a 5-day expansion period, there was a consolidation period of 15 days, following which the rats were killed. Histomorphometric examination was performed to determine the number of osteoclasts, osteoblasts, and capillaries, the number and intensity of inflammatory cells, and new bone formation.
RESULTS
New bone formation, number of capillaries, and the ratio of inflammatory cells in maxillary sutures were higher in the GB group than in the other groups. Statistical analysis demonstrated that the GB group had more osteoblasts and osteoclasts than the other groups.
CONCLUSIONS
GB may hasten new bone regeneration in RME and prevent relapse after RME.
目的
研究银杏叶提取物对快速上颌扩张（RME）的影响。
研究设计
将 24 只大鼠随机分为 3 组：仅扩张组（EO）、扩张加银杏叶提取物组（GB）和未扩张组（NE）。上颌切牙上安装扩张器。扩张期 5 天后，有 15 天的巩固期，然后处死大鼠。进行组织形态计量学检查以确定破骨细胞、成骨细胞和毛细血管的数量、炎症细胞的数量和强度以及新骨形成。
结果
GB 组新骨形成、上颌缝内毛细血管数量和炎症细胞比例均高于其他组。统计分析表明，GB 组的成骨细胞和破骨细胞多于其他组。
结论
GB 可能加速 RME 中新骨的再生，并防止 RME 后的复发。
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