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通过分析玻璃体液中的钾来估计死后间隔时间:重复采样能否提高准确性?

Estimation of the postmortem interval by analyzing potassium in the vitreous humor: could repetitive sampling enhance accuracy?

作者信息

Mihailovic Zoran, Atanasijevic Tatjana, Popovic Vesna, Milosevic Miroslav B, Sperhake Jan P

机构信息

Institute of Forensic Medicine, Milovan Milovanovic, School of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

Am J Forensic Med Pathol. 2012 Dec;33(4):400-3. doi: 10.1097/PAF.0b013e31826627d0.

Abstract

The relationship between the postmortem interval and the potassium concentration in the vitreous humor has been described by different authors. A limitation of most previous studies might be that all of the vitreous humor has been extracted in 1 sample from different subjects and that the sample was therefore inhomogeneous. In 32 traumatic deaths with known postmortem intervals, small quantities of vitreous humor have been sampled repetitively in 3-hour interval. The bodies were stored at 20°C. The average concentrations of potassium in relation to the postmortem interval were 6.11 to 14.46 mmol/L. An equation that allows accurate prediction of the postmortem interval was established: postmortem interval (h) = 2.749 × [K] - 11.978.

摘要

不同作者描述了死后间隔时间与玻璃体液中钾浓度之间的关系。大多数先前研究的一个局限性可能是,所有玻璃体液都是从不同受试者的一个样本中提取的,因此该样本是不均匀的。在32例已知死后间隔时间的外伤性死亡案例中,每隔3小时重复采集少量玻璃体液。尸体保存在20°C的环境中。与死后间隔时间相关的钾平均浓度为6.11至14.46 mmol/L。建立了一个能够准确预测死后间隔时间的方程:死后间隔时间(小时)=2.749×[钾浓度] - 11.978 。

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