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Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth.
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2
Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway.
J Neurosci. 2008 Jul 30;28(31):7900-10. doi: 10.1523/JNEUROSCI.0617-08.2008.
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Myocilin is involved in NgR1/Lingo-1-mediated oligodendrocyte differentiation and myelination of the optic nerve.
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LOTUS suppresses axon growth inhibition by blocking interaction between Nogo receptor-1 and all four types of its ligand.
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LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex.
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Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation.
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Plexina2 and CRMP2 Signaling Complex Is Activated by Nogo-A-Liganded Ngr1 to Restrict Corticospinal Axon Sprouting after Trauma.
J Neurosci. 2019 Apr 24;39(17):3204-3216. doi: 10.1523/JNEUROSCI.2996-18.2019. Epub 2019 Feb 25.

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Correlation of peripheral olfactomedin 1 with Alzheimer's disease and cognitive functions.
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Genome-wide meta-analyses of non-response to antidepressants identify novel loci and potential drugs.
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Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis.
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Organ aging signatures in the plasma proteome track health and disease.
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Secreted Glycoproteins That Regulate Synaptic Function: the Dispatchers in the Central Nervous System.
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本文引用的文献

1
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.
Nat Neurosci. 2012 Mar 11;15(5):703-12. doi: 10.1038/nn.3070.
2
Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins.
Invest Ophthalmol Vis Sci. 2011 Apr 20;52(5):2584-92. doi: 10.1167/iovs.10-6356. Print 2011 Apr.
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Emerging functions of myelin-associated proteins during development, neuronal plasticity, and neurodegeneration.
FASEB J. 2011 Feb;25(2):463-75. doi: 10.1096/fj.10-162792. Epub 2010 Nov 8.
4
Functions of Nogo proteins and their receptors in the nervous system.
Nat Rev Neurosci. 2010 Dec;11(12):799-811. doi: 10.1038/nrn2936. Epub 2010 Nov 3.
5
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition.
J Neurosci. 2010 May 12;30(19):6607-12. doi: 10.1523/JNEUROSCI.5147-09.2010.
6
Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals.
Curr Biol. 2009 Dec 29;19(24):2086-90. doi: 10.1016/j.cub.2009.10.051. Epub 2009 Dec 3.
7
Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology.
Mol Neurobiol. 2009 Oct;40(2):122-38. doi: 10.1007/s12035-009-8076-x. Epub 2009 Jun 26.
8
Blockade of Nogo receptor ligands promotes functional regeneration of sensory axons after dorsal root crush.
J Neurosci. 2009 May 13;29(19):6285-95. doi: 10.1523/JNEUROSCI.5885-08.2009.
9
Nogo-Nogo receptor signalling in PNS axon outgrowth and pathfinding.
Mol Cell Neurosci. 2009 Apr;40(4):401-9. doi: 10.1016/j.mcn.2008.10.009. Epub 2008 Nov 8.
10
Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway.
J Neurosci. 2008 Jul 30;28(31):7900-10. doi: 10.1523/JNEUROSCI.0617-08.2008.

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