ACR Image Metrix, Philadelphia, PA, USA.
Radiology. 2012 Oct;265(1):51-8. doi: 10.1148/radiol.12110600. Epub 2012 Aug 24.
To assess diagnostic performance of dedicated breast magnetic resonance (MR) imaging at breast imaging centers by using a dedicated 1.5-T breast MR system that used high-spatial-resolution, high-contrast-resolution spiral trajectory acquisitions.
The study was institutional review board approved and HIPAA compliant, with waiver of informed consent. Diagnostic performance was retrospectively assessed for 934 consecutive screening (n=347) and diagnostic (n=587) examinations performed from April 2006 to December 2007 in women aged 25-89 years old from four sites for which dedicated breast MR imaging reports and ground truth (biopsy for cancer cases, 1-year follow-up with negative results for cases with negative findings) were available. The sensitivity, specificity, and receiver operating characteristic (ROC) for breast MR imaging were determined.
The sensitivity and specificity for the dedicated breast MR imaging system were 92% (92 of 100) and 88.8% (741 of 834). For all cases, the negative predictive value (NPV) was 98.9% (741 of 749). The NPV for screening cases was 100% (326 of 326). The area under the ROC curve was 0.942. Of the 93 cases with false-positive findings seen at dedicated breast MR imaging, 25 (27%) were high-risk histologic findings for which excision is often recommended. The false-positive rate was 93 of 834 (11.2%) for all cases, but only 16 of 326 (4.9%) for the screening cohort.
High accuracy was achieved by using dedicated breast MR imaging.
使用高空间分辨率、高对比分辨率螺旋轨迹采集的专用 1.5T 乳腺磁共振（MR）系统评估乳腺影像中心的专用乳腺 MR 成像的诊断性能。
本研究经机构审查委员会批准，并符合 HIPAA 规定，豁免知情同意。对 2006 年 4 月至 2007 年 12 月在四个地点进行的 934 例连续筛查（n=347）和诊断（n=587）检查进行回顾性评估，这些检查的女性年龄为 25-89 岁，并且可获得专用乳腺 MR 成像报告和金标准（癌症病例活检，阴性发现病例的 1 年随访结果为阴性）。确定了乳腺 MR 成像的敏感性、特异性和受试者工作特征（ROC）。
专用乳腺 MR 成像系统的敏感性和特异性分别为 92%（100 例中的 92 例）和 88.8%（834 例中的 741 例）。对于所有病例，阴性预测值（NPV）为 98.9%（749 例中的 741 例）。筛查病例的 NPV 为 100%（326 例中的 326 例）。ROC 曲线下面积为 0.942。在专用乳腺 MR 成像中发现的 93 例假阳性病例中，25 例（27%）为常建议切除的高危组织学发现。所有病例的假阳性率为 93 例/834 例（11.2%），但仅为筛查队列的 16 例/326 例（4.9%）。
使用专用乳腺 MR 成像可获得高准确性。
