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鳞状上皮为主型畸胎样肾母细胞瘤

Squamous predominant teratoid Wilms' tumor.

作者信息

Yadav Yogesh Kumar, Sharma Uma, Gupta Kusum, Arora Rashmi

机构信息

Department of Pathology, V.M.M.C and Safdarjung Hospital, New Delhi- 29, India.

出版信息

J Lab Physicians. 2012 Jan;4(1):50-2. doi: 10.4103/0974-2727.98675.

DOI:10.4103/0974-2727.98675
PMID:22923925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3425268/
Abstract

Teratoid Wilms tumor is an unusual histological variant of nephroblastoma with predominant heterologous component. Frequently present components include adipose tissue, glial tissue, muscle, cartilage or bone. The presence of squamous epithelial component on the other hand is rarely reported. We describe a case of unilateral teratoid Wilms' tumor in a 2-year-old boy with lung metastasis. In this case, tumor showed the familiar triphasic histologic pattern of nephroblastoma along with extensive squamous epithelial component.

摘要

畸胎样肾母细胞瘤是肾母细胞瘤一种不常见的组织学变异型,以异源性成分占主导。常见的成分包括脂肪组织、神经胶质组织、肌肉、软骨或骨。另一方面,鳞状上皮成分的存在很少被报道。我们描述了一例2岁男孩单侧畸胎样肾母细胞瘤伴肺转移的病例。在该病例中,肿瘤呈现出肾母细胞瘤常见的三相组织学模式以及广泛的鳞状上皮成分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/1a669364610a/JLP-4-50-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/112102a32d7b/JLP-4-50-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/e3c997ae59a9/JLP-4-50-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/7b688a475848/JLP-4-50-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/1a669364610a/JLP-4-50-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/112102a32d7b/JLP-4-50-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/e3c997ae59a9/JLP-4-50-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/7b688a475848/JLP-4-50-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/951a/3425268/1a669364610a/JLP-4-50-g004.jpg

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Squamous predominant teratoid Wilms' tumor.鳞状上皮为主型畸胎样肾母细胞瘤
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Teratoid Wilms Tumor and Classical Wilms Tumor: A Retrospective 10-Year Single-Center Study and Literature Review.畸胎样肾母细胞瘤与经典型肾母细胞瘤:一项为期10年的单中心回顾性研究及文献综述
Front Surg. 2022 Feb 2;8:781060. doi: 10.3389/fsurg.2021.781060. eCollection 2021.
2
Extrarenal teratoma with nephroblastoma in the retroperitoneum: Case report and literature review.腹膜后肾外畸胎瘤合并肾母细胞瘤:病例报告及文献复习
Medicine (Baltimore). 2017 Nov;96(46):e8670. doi: 10.1097/MD.0000000000008670.
3
promotes the proliferation, invasion and migration of Wilms' tumor and can be used as a prognostic factor.

本文引用的文献

1
Teratoid Wilms' tumor: case report of a rare variant that can mimic aggressive biology during chemotherapy.畸胎瘤样 Wilms 瘤:一例罕见变异型病例报告,其在化疗期间可模拟侵袭性生物学行为。
J Pediatr Surg. 2011 Dec;46(12):e1-6. doi: 10.1016/j.jpedsurg.2011.09.049.
2
Distinct features of teratoid Wilms tumor.畸胎瘤性 Wilms 瘤的特征。
J Pediatr Surg. 2010 Oct;45(10):e13-9. doi: 10.1016/j.jpedsurg.2010.06.035.
3
Extrarenal teratoid Wilms' tumor: two cases in unusual locations, one associated with elevated serum AFP.肾外胚层组织来源的畸胎瘤性肾母细胞瘤:两例罕见部位发病病例,其中一例伴有血清 AFP 升高。
促进肾母细胞瘤的增殖、侵袭和迁移,可作为一个预后因素。
Onco Targets Ther. 2017 Feb 16;10:955-963. doi: 10.2147/OTT.S127419. eCollection 2017.
4
The roles of microRNAs in Wilms' tumors.微小RNA在肾母细胞瘤中的作用。
Tumour Biol. 2016 Feb;37(2):1445-50. doi: 10.1007/s13277-015-4514-8. Epub 2015 Dec 3.
Pathol Int. 2010 Jan;60(1):35-41. doi: 10.1111/j.1440-1827.2009.02468.x.
4
A unilateral teratoid Wilms' tumor with raised serum alpha-fetoprotein level.一例血清甲胎蛋白水平升高的单侧畸胎瘤样肾母细胞瘤。
Indian J Pathol Microbiol. 2007 Apr;50(2):317-9.
5
Teratoid Wilms' tumor: a case report with literature review.畸胎样肾母细胞瘤:一例报告并文献复习
J Pediatr Surg. 2006 Oct;41(10):1759-63. doi: 10.1016/j.jpedsurg.2006.05.045.
6
Teratoid Wilms' tumor: a case report.畸胎样肾母细胞瘤:一例报告
Turk J Pediatr. 2000 Jul-Sep;42(3):242-5.
7
Teratoid Wilms' tumor.
Cancer. 1984 May 1;53(9):1936-42. doi: 10.1002/1097-0142(19840501)53:9<1936::aid-cncr2820530922>3.0.co;2-w.
8
Wilms' tumor and other renal tumors of childhood: a selective review from the National Wilms' Tumor Study Pathology Center.儿童肾母细胞瘤及其他肾脏肿瘤:来自国家肾母细胞瘤研究病理中心的选择性综述
Hum Pathol. 1983 Jun;14(6):481-92. doi: 10.1016/s0046-8177(83)80003-3.
9
Extracellular matrix and epithelial differentiation of Wilms' tumor.肾母细胞瘤的细胞外基质与上皮分化
Am J Pathol. 1985 Jan;118(1):96-107.
10
Teratoid Wilms' tumor: the St Jude experience.畸胎样肾母细胞瘤:圣裘德儿童研究医院的经验
J Pediatr Surg. 1988 Dec;23(12):1131-4. doi: 10.1016/s0022-3468(88)80328-2.