Chandrashekar Vani, Soni Mamta
Department of Hematology, Apollo Hospitals, 21, Greams Lane, Off Greams Road, Chennai, Tamil Nadu, India.
J Lab Physicians. 2012 Jan;4(1):59-61. doi: 10.4103/0974-2727.98679.
Erythrophagocytosis is a relatively rare observation on blood smears. It has been reported in auto immune hemolytic anemias and sporadically in few other conditions. Here, we report a case of florid erythrophagocytosis with severe anemia following a viral infection in an 18-year-old girl. Her complete blood count (CBC) revealed hemoglobin of 3.6 gm/dl and a hematocrit of 10%. The peripheral smear showed erythrophagocytosis by neutrophils and rosetting of erythrocytes around neutrophils. The direct Coombs test and direct Donath- Landsteiner tests were positive.
红细胞吞噬现象在血涂片上相对少见。在自身免疫性溶血性贫血中曾有报道,在其他少数情况下也偶有发现。在此,我们报告一例18岁女孩在病毒感染后出现明显红细胞吞噬现象并伴有严重贫血的病例。她的全血细胞计数(CBC)显示血红蛋白为3.6克/分升,血细胞比容为10%。外周血涂片显示中性粒细胞吞噬红细胞以及红细胞围绕中性粒细胞形成花环状。直接抗人球蛋白试验和直接Donath-Landsteiner试验均为阳性。