Idriss Munir H, Temam Fuad, Woldeyes Mihretu
Department of Dermatology/Venereology, Addis Ababa University School of Medicine, P.O.BOX 9086,Addis Ababa, Ethiopia.
Ethiop Med J. 2012 Apr;50(2):193-200.
Langerhans' cell histiocytosis represents a diverse group of rare disorders characterized by proliferation and infiltration of various organs by bone marrow-derived abnormal Langerhans' cells. These diorders exhibit varied patterns of organ involvement, age distribution, prognosis and clinical manifestation. Here in we discuss an adult presentation of the disease in a 43 years old lady and summarize the latest recommendations regarding the classification, pathogenesis, work up and treatment of adult patients with these disorders.
朗格汉斯细胞组织细胞增多症是一组罕见的疾病，其特征是骨髓来源的异常朗格汉斯细胞在各个器官中增殖和浸润。这些疾病表现出不同的器官受累模式、年龄分布、预后和临床表现。在此，我们讨论一名43岁女性成人患者的该疾病表现，并总结关于这些疾病成年患者的分类、发病机制、检查和治疗的最新建议。
