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角质层对整个皮肤机械性能的影响,由一个计算皮肤模型预测。

Influence of Stratum Corneum on the entire skin mechanical properties, as predicted by a computational skin model.

机构信息

Consultant, Paris, France.

出版信息

Skin Res Technol. 2013 Feb;19(1):42-6. doi: 10.1111/j.1600-0846.2012.00664.x. Epub 2012 Aug 23.

Abstract

BACKGROUND/PURPOSE: Skin mechanical properties are globally well described. The aim of this paper is to evaluate, by means of a numerical model, the influence of Stratum Corneum (SC) on skin folding resulting from an in-plane compression.

METHODS

A computational skin model was developed where skin is divided into three layers (SC, epidermis and upper dermis, and deep dermis) of different thicknesses and elastic moduli. Skin surface deformation, consecutive to the application of a given surface compression, was computed by minimizing the mechanical energy of the multi-layered tissue. Influence of SC thickness and elastic modulus on skin buckling is presented.

RESULTS

Varying both SC thickness and elastic modulus has a marked influence on both wavelength and amplitude of the skin's surface folds. These two parameters display a logarithmic variation versus SC elastic modulus.

CONCLUSION

Although representing about one hundredth of the total skin thickness, SC has a marked influence on the skin mechanical properties.

摘要

背景/目的:皮肤的机械性能已得到全面描述。本文旨在通过数值模型评估表皮层(SC)对平面压缩引起的皮肤褶皱的影响。

方法

建立了一个计算皮肤模型,其中皮肤分为三个不同厚度和弹性模量的层(SC、表皮和上真皮以及真皮深层)。通过最小化多层组织的机械能来计算皮肤表面在施加给定表面压缩后的变形。介绍了 SC 厚度和弹性模量对皮肤起皱的影响。

结果

改变 SC 的厚度和弹性模量都会显著影响皮肤表面褶皱的波长和振幅。这两个参数与 SC 弹性模量呈对数变化。

结论

尽管 SC 仅占皮肤总厚度的百分之一,但它对皮肤的机械性能有显著影响。

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