Friedland J S, Iveson T J, Fraise A P, Winearls C G, Selkon J B, Oliver D O
Renal Unit, Churchill Hospital, Oxford, UK.
J Antimicrob Chemother. 1990 Dec;26 Suppl F:77-81. doi: 10.1093/jac/26.suppl_f.77.
In a prospective, randomized, controlled trial in 40 patients, intraperitoneal ciprofloxacin was shown to be as effective as the currently recommended regimen of intraperitoneal vancomycin and gentamicin for the treatment of CAPD peritonitis. There was one treatment failure in the ciprofloxacin arm and four in the comparative arm. A single drug regimen is preferred by patients. The intraperitoneal route of administration of ciprofloxacin therapy has advantages over the oral route.
在一项针对40例患者的前瞻性、随机、对照试验中，腹腔内使用环丙沙星治疗持续性非卧床腹膜透析（CAPD）相关性腹膜炎，其疗效与目前推荐的腹腔内使用万古霉素和庆大霉素的方案相当。环丙沙星组有1例治疗失败，对照组有4例。患者更倾向于单一药物治疗方案。环丙沙星腹腔内给药途径比口服途径更具优势。
