Gün Ismet, Oner Oznur, Bodur Serkan, Ozdamar Ozkan, Atay Vedat
Department of Obstetrics and Gynecology, GATA Haydarpaşa Training Hospital, İstanbul,Turkey.
Med Glas (Zenica). 2012 Aug;9(2):268-72.
To evaluate an association of adenomyosis with endometrial cancer and to determine the frequency of adenomyosis at hysterectomy specimens.
This study was carried out retrospectively on pathologic specimens of hysterectomies. A total of 472 women in the period 2007-2011 enrolled to the study. All pathologies seen in hysterectomy specimens were noted. The frequency of adenomyosis and the accompanying pathologies were determined. These women were categorized into two groups according to the presence of adenomyosis. The incidence of adenomyosis was analyzed together with the endometrial cancer.
The incidence of adenomyosis was 20.8% at hysterectomy specimens. There was no statistically significant difference between the mean age of the two groups (p = 0.069). There were 98 cases with adenomyosis and the only pathologic finding was adenomyosis, in 28 (28.5%) cases. The most common accompanying pathologies with adenomyosis were uterine myomas in 51 (52%), uterine polyps in 16 (16.3%) and endometrial carcinomas in 11 (11.2%) cases. However, statistically significant association of the presence of adenomyosis with uterine myoma (p = 0.227) and endometrial polyps (p = 0.997) and endometrial carcinoma (p = 0.771) was not found.
In hysterectomy specimens, no statistically significant difference was determined between the groups with and without adenomyosis in terms of co-occurrence with endometrial carcinoma.
评估子宫腺肌病与子宫内膜癌的关联，并确定子宫切除标本中子宫腺肌病的发生率。
本研究对子宫切除的病理标本进行回顾性研究。2007年至2011年期间共有472名女性纳入研究。记录子宫切除标本中所见的所有病理情况。确定子宫腺肌病的发生率及伴随的病理情况。根据是否存在子宫腺肌病将这些女性分为两组。分析子宫腺肌病的发生率与子宫内膜癌的情况。
子宫切除标本中子宫腺肌病的发生率为20.8%。两组的平均年龄之间无统计学显著差异（p = 0.069）。有98例子宫腺肌病患者，其中28例（28.5%）的唯一病理发现是子宫腺肌病。子宫腺肌病最常见的伴随病理情况是子宫肌瘤，共51例（52%），子宫息肉16例（16.3%），子宫内膜癌11例（11.2%）。然而，未发现子宫腺肌病的存在与子宫肌瘤（p = 0.227）、子宫内膜息肉（p = 0.997）及子宫内膜癌（p = 0.771）之间存在统计学显著关联。
在子宫切除标本中，有子宫腺肌病组与无子宫腺肌病组在与子宫内膜癌同时发生方面未发现统计学显著差异。
