Genc M, Celik E, Eskicioglu F, Bahar Gur E, Kurtulmus S, Gulec E, Guclu S
Clin Exp Obstet Gynecol. 2016;43(4):500-503.
The aim of this study was to stress the importance of performing a thorough uterine assessment before selecting an organ- sparing surgery in patients presenting with uterine prolapse and no other complaints.
This study included a total of 111 participants who presented with pelvic organ prolapse and underwent hysterectomy for grades 3-4 uterine prolapse. The posthysterectomy histopathology results were classified as benign (atrophic endometrium, proliferative or secretory endometrium) or pathologic (endometrial hyperplasia, endometrial polyp, adenomyosis, myoma uteri, and endometrium carcinoma).
Of the 111 patients enrolled in this study, 23 (20.2%) had endometrial hyperplasia, eight (7.2%) had endometrial polyps, 30 (27%) had uterine fibroids, and 20 (18%) had adenomyosis.
There may be premalignant lesions of the endometrium in both premenopausal and postmenopausal women presenting with uterine prolapse and no other symptoms. A chronic inflammatory process resulting from the extra-vaginal location of the uterus may play a role in the development of these lesions. Further studies are needed on this subject.
本研究的目的是强调在为子宫脱垂且无其他不适的患者选择保留器官手术前，进行全面子宫评估的重要性。
本研究共纳入111例盆腔器官脱垂患者，这些患者因3-4度子宫脱垂接受了子宫切除术。子宫切除术后的组织病理学结果分为良性（萎缩性子宫内膜、增殖期或分泌期子宫内膜）或病理性（子宫内膜增生、子宫内膜息肉、子宫腺肌病、子宫肌瘤和子宫内膜癌）。
本研究纳入的111例患者中，23例（20.2%）有子宫内膜增生，8例（7.2%）有子宫内膜息肉，30例（27%）有子宫肌瘤，20例（18%）有子宫腺肌病。
子宫脱垂且无其他症状的绝经前和绝经后女性可能存在子宫内膜癌前病变。子宫阴道外位置导致的慢性炎症过程可能在这些病变的发生中起作用。对此主题需要进一步研究。
