NeuroSpineClinic, Suite 7, Level 7 Prince of Wales Private Hospital, Sydney, Australia.
Orthop Surg. 2012 Aug;4(3):156-65. doi: 10.1111/j.1757-7861.2012.00185.x.
To evaluate the properties of a combination bone graft consisting of biphasic calcium phosphate ceramic, polyetheretherketone (PEEK) cage in one- and two-level surgery.
Over a 12-month time period, a prospective single surgeon series of 75 patients were included in the study and 58 patients selected based on adequate data points. From these 58 patients, 32 were supplemented with anterior plate fixation and 26 patients without plating. Duration of clinical follow-up was a mean of 12.4 months (range, 6-26 months) in the Plated Group and 10.5 months (range, 6-21 months) in the Non-Plated Group.
A 100% fusion rate with nil graft related complications was achieved in the Plated group compared with 96.2% fusion and 11.5% subsidence rates reported in the Non-Plated group. Patients in both groups experienced statistically significant improvement in pain and functional outcomes compared to their pre-operative status; however, there was no significant difference in outcome between the Plated and Non-Plated Groups.
Biphasic calcium phosphate ceramic contained within a PEEK cage is an effective implant for use in anterior cervical surgery with high fusion rates and good clinical outcome.
评估由双相磷酸钙陶瓷和聚醚醚酮(PEEK)笼组成的组合骨移植物在单节段和双节段手术中的特性。
在 12 个月的时间内,前瞻性地纳入了一位外科医生的 75 例患者系列研究,根据充分的数据点选择了 58 例患者。在这些 58 例患者中,32 例接受了前路钢板固定,26 例未接受钢板固定。在有钢板组中,临床随访的平均时间为 12.4 个月(范围,6-26 个月),在无钢板组中为 10.5 个月(范围,6-21 个月)。
在有钢板组中,融合率达到 100%,无移植物相关并发症,而在无钢板组中,融合率为 96.2%,沉降率为 11.5%。两组患者的疼痛和功能结局均较术前显著改善,但钢板组和无钢板组之间的结果无显著差异。
双相磷酸钙陶瓷置于 PEEK 笼中是一种有效的用于前路颈椎手术的植入物,具有较高的融合率和良好的临床结果。