颈椎前路椎间盘切除融合术中的骨移植替代物
Bone graft substitutes in anterior cervical discectomy and fusion.
作者信息
Chau Anthony M T, Mobbs Ralph J
机构信息
University of New South Wales, Sydney, Australia.
出版信息
Eur Spine J. 2009 Apr;18(4):449-64. doi: 10.1007/s00586-008-0878-4. Epub 2009 Jan 17.
Abstract
Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in human clinical trials, considering allograft-based, synthetic, factor- and cell-based technologies.
摘要
前路颈椎间盘切除融合术是治疗疼痛和/或神经功能缺损且保守治疗无效患者的常见外科手术。几十年来，取自髂嵴的自体骨移植一直被用作颈椎融合的基质。然而，患者对供区并发症的不满促使人们寻找替代技术。我们进行了一项文献综述，考察了在人体临床试验中评估的现有移植选择的进展，涵盖基于同种异体移植物、合成材料、因子和细胞的技术。
相似文献
1
Bone graft substitutes in anterior cervical discectomy and fusion.颈椎前路椎间盘切除融合术中的骨移植替代物
Eur Spine J. 2009 Apr;18(4):449-64. doi: 10.1007/s00586-008-0878-4. Epub 2009 Jan 17.
2
Stand-alone interbody cage versus anterior cervical plate for treatment of cervical disc herniation: sequential changes in cage subsidence.单独椎间融合器与颈椎前路钢板治疗颈椎间盘突出症：融合器下沉的连续变化
J Clin Neurosci. 2008 Sep;15(9):1017-22. doi: 10.1016/j.jocn.2007.05.011. Epub 2008 Jul 23.
3
The efficacy of the synthetic interbody cage and Grafton for anterior cervical fusion.合成椎间融合器与Grafton用于颈椎前路融合术的疗效。
Spine (Phila Pa 1976). 2009 Aug 1;34(17):E591-5. doi: 10.1097/BRS.0b013e3181ab8b9a.
4
A novel source of cancellous autograft for ACDF surgery: the manubrium.一种用于颈椎前路减压融合术（ACDF）的新型松质骨自体移植来源：胸骨柄。
J Spinal Disord Tech. 2007 Feb;20(1):36-41. doi: 10.1097/01.bsd.0000211230.89554.5c.
5
Long term outcome of anterior cervical discectomy and fusion using coral grafts.使用珊瑚移植物进行颈椎前路椎间盘切除融合术的长期疗效
Acta Neurochir (Wien). 2008 Dec;150(12):1249-56; discussion 1256. doi: 10.1007/s00701-008-0140-1. Epub 2008 Nov 11.
6
A prospective clinical and radiographic 12-month outcome study of patients undergoing single-level anterior cervical discectomy and fusion for symptomatic cervical degenerative disc disease utilizing a novel viable allogeneic, cancellous, bone matrix (trinity evolution™) with a comparison to historical controls.一项针对有症状的颈椎退行性椎间盘疾病患者进行单节段颈椎前路椎间盘切除融合术的前瞻性临床和影像学12个月结局研究，使用一种新型的活性同种异体松质骨基质（Trinity Evolution™），并与历史对照进行比较。
Eur Spine J. 2016 Jul;25(7):2233-8. doi: 10.1007/s00586-016-4414-7. Epub 2016 Feb 5.
7
Use of patella allograft for anterior cervical diskectomy and fusion.同种异体髌骨在颈椎前路椎间盘切除融合术中的应用。
J Spinal Disord Tech. 2009 Aug;22(6):392-8. doi: 10.1097/BSD.0b013e3181844d8e.
8
Is tutobone an efficient alternative to other implants used in anterior cervical discectomy and fusion surgeries?Tutobone（突托邦）是颈椎前路椎间盘切除融合手术中使用的其他植入物的有效替代品吗？
Br J Neurosurg. 2017 Jun;31(3):340-344. doi: 10.1080/02688697.2017.1297362. Epub 2017 Mar 6.
9
Three- and four-level anterior cervical discectomy and fusion with plate fixation: a prospective study.三节段和四节段颈椎前路椎间盘切除融合钢板内固定术：一项前瞻性研究
Spine (Phila Pa 1976). 2000 Aug 15;25(16):2040-4; discussion 2045-6. doi: 10.1097/00007632-200008150-00007.
10
The design evolution of interbody cages in anterior cervical discectomy and fusion: a systematic review.颈椎前路椎间盘切除融合术中椎间融合器的设计演变：一项系统评价
BMC Musculoskelet Disord. 2015 Apr 25;16:99. doi: 10.1186/s12891-015-0546-x.
引用本文的文献
1
Fusion outcomes of structural bone allograft in cervical and lumbar spine surgery: analysis of 147 patients over a decade of follow-up.颈椎和腰椎手术中结构性骨移植的融合结果：对147例患者进行十年随访的分析
J Spine Surg. 2025 Jun 27;11(2):256-268. doi: 10.21037/jss-24-130. Epub 2025 Apr 28.
2
Early clinical experience with a new supercritical CO virus-inactivated bone paste allograft in cervical interbody fusion.新型超临界二氧化碳病毒灭活骨糊同种异体移植物用于颈椎椎间融合的早期临床经验。
Eur Spine J. 2025 Jun 4. doi: 10.1007/s00586-025-08851-8.
3
Hydroxyapatite/collagen composite graft for anterior cervical discectomy and fusion: a comparison with Iliac crest bone graft.用于颈椎前路椎间盘切除融合术的羟基磷灰石/胶原蛋白复合移植物：与髂嵴骨移植的比较。
BMC Musculoskelet Disord. 2025 Jun 3;26(1):552. doi: 10.1186/s12891-025-08782-x.
4
Efficacy of an allograft cellular bone matrix as an alternative to autograft in anterior cervical discectomy and fusion: radiological results & safety.同种异体脱细胞骨基质作为颈椎前路椎间盘切除融合术中自体骨替代物的疗效：影像学结果与安全性
J Spine Surg. 2024 Sep 23;10(3):372-385. doi: 10.21037/jss-23-142. Epub 2024 Aug 7.
5
Clinical Effectiveness of Anterior Cervical Discectomy and Fusion Using Tritanium C Anterior Cervical Cage vs. PEEK Cage.使用Tritanium C颈椎前路椎间融合器与聚醚醚酮（PEEK）椎间融合器行颈椎前路椎间盘切除融合术的临床疗效
Spine Surg Relat Res. 2024 Feb 14;8(4):399-408. doi: 10.22603/ssrr.2023-0140. eCollection 2024 Jul 27.
6
Safety and Efficacy of Zero-Profile Polyetheretherketone (PEEK) Cages Filled with Biphasic Calcium Phosphate (BCP) in Anterior Cervical Discectomy and Fusion (ACDF): A Case Series.零轮廓聚醚醚酮（PEEK）椎间融合器填充双相磷酸钙（BCP）在前路颈椎间盘切除融合术（ACDF）中的安全性和有效性：病例系列
J Clin Med. 2024 Mar 26;13(7):1919. doi: 10.3390/jcm13071919.
7
Structural Allograft Versus Mechanical Interbody Devices Augmented With Osteobiologics in Anterior Cervical Discectomy and Fusion: A Systematic Review.前路颈椎间盘切除融合术中结构性同种异体移植物与添加骨生物制剂的机械椎间融合器的比较：一项系统评价
Global Spine J. 2024 Feb;14(2_suppl):34S-42S. doi: 10.1177/21925682231171857.
8
Efficacy of Allograft Versus Bioactive Glass-Ceramic Cage in Anterior Cervical Discectomy and Fusion: A Randomized Controlled Study.同种异体移植物与生物活性玻璃陶瓷椎间融合器在前路颈椎间盘切除融合术中的疗效：一项随机对照研究。
Global Spine J. 2025 Mar;15(2):981-992. doi: 10.1177/21925682231219225. Epub 2023 Nov 29.
9
Factors influencing cage subsidence in anterior cervical corpectomy and discectomy: a systematic review.影响前路颈椎椎体次全切融合术和椎间盘切除术 cage 沉降的因素：系统评价。
Eur Spine J. 2023 Mar;32(3):957-968. doi: 10.1007/s00586-023-07530-w. Epub 2023 Jan 28.
10
A Bibliometric Analysis of the Top 100 Cited Articles in Anterior Cervical Discectomy and Fusion.颈椎前路椎间盘切除融合术领域被引频次最高的100篇文章的文献计量分析
J Pain Res. 2022 Oct 11;15:3137-3156. doi: 10.2147/JPR.S375720. eCollection 2022.
本文引用的文献
1
Anterior cervical graftless fusion for soft disc protrusion. A review of 509 disc excisions in 476 patients.前路无植骨融合术治疗软性椎间盘突出症：476例患者509次椎间盘切除术的回顾
J Clin Neurosci. 1998 Apr;5(2):172-7. doi: 10.1016/s0967-5868(98)90033-9.
2
The safety and efficacy of anterior cervical discectomy and fusion with polyetheretherketone spacer and recombinant human bone morphogenetic protein-2: a review of 200 patients.前路颈椎间盘切除融合术联合聚醚醚酮椎间融合器及重组人骨形态发生蛋白-2的安全性和有效性：200例患者的回顾性研究
J Neurosurg Spine. 2008 Jun;8(6):529-35. doi: 10.3171/SPI/2008/8/6/529.
3
Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collar.单节段颈椎前路椎间盘切除及同种异体骨融合且未使用钢板固定或佩戴颈托后的影像学和临床结果
J Neurosurg Spine. 2008 May;8(5):420-8. doi: 10.3171/SPI/2008/8/5/420.
4
Anterior cervical fusion with interbody cage containing beta-tricalcium phosphate augmented with plate fixation: a prospective randomized study with 2-year follow-up.前路颈椎融合术，采用含β-磷酸三钙的椎间融合器并辅以钢板固定：一项为期2年随访的前瞻性随机研究。
Eur Spine J. 2008 May;17(5):698-705. doi: 10.1007/s00586-008-0643-8. Epub 2008 Feb 27.
5
High graft resorption rates with dense cancellous allograft in anterior cervical discectomy and fusion.颈椎前路椎间盘切除融合术中使用致密松质骨同种异体骨时移植骨吸收率高。
Spine (Phila Pa 1976). 2007 Dec 15;32(26):2980-4. doi: 10.1097/BRS.0b013e31815cd464.
6
Multilevel anterior cervical fusion using a collagen-hydroxyapatite matrix with iliac crest bone marrow aspirate: an 18-month follow-up study.使用胶原蛋白-羟基磷灰石基质联合髂嵴骨髓抽吸物进行多节段颈椎前路融合术：一项18个月的随访研究。
Neurosurgery. 2007 Nov;61(5):963-70; discussion 970-1. doi: 10.1227/01.neu.0000303192.64802.c6.
7
Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion.同种异体移植物联合骨形态发生蛋白与髂嵴自体骨移植在前路颈椎间盘切除融合术中的前瞻性非随机比较。
Spine J. 2008 May-Jun;8(3):426-35. doi: 10.1016/j.spinee.2006.12.006. Epub 2007 Mar 7.
8
Effect of autologous platelet gel on early and late graft fusion in anterior cervical spine surgery.自体血小板凝胶对颈椎前路手术中早期和晚期植骨融合的影响。
J Neurosurg Spine. 2007 Nov;7(5):496-502. doi: 10.3171/SPI-07/11/496.
9
Use of the clavicle in anterior cervical discectomy/corpectomy fusion procedures: cadaveric feasibility study.锁骨在前路颈椎间盘切除术/椎体次全切除融合手术中的应用：尸体可行性研究
Childs Nerv Syst. 2008 Mar;24(3):337-41. doi: 10.1007/s00381-007-0433-3. Epub 2007 Jul 18.
10
Bone allografts: What they can offer and what they cannot.骨移植：它们能提供什么以及不能提供什么。
J Bone Joint Surg Br. 2007 May;89(5):574-9. doi: 10.1302/0301-620X.89B5.19039.
Zotero 插件