颈椎前路椎间盘切除融合术中的骨移植替代物
Bone graft substitutes in anterior cervical discectomy and fusion.
作者信息
Chau Anthony M T, Mobbs Ralph J
机构信息
University of New South Wales, Sydney, Australia.
出版信息
Eur Spine J. 2009 Apr;18(4):449-64. doi: 10.1007/s00586-008-0878-4. Epub 2009 Jan 17.
Abstract
Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in human clinical trials, considering allograft-based, synthetic, factor- and cell-based technologies.
摘要
前路颈椎间盘切除融合术是治疗疼痛和/或神经功能缺损且保守治疗无效患者的常见外科手术。几十年来，取自髂嵴的自体骨移植一直被用作颈椎融合的基质。然而，患者对供区并发症的不满促使人们寻找替代技术。我们进行了一项文献综述，考察了在人体临床试验中评估的现有移植选择的进展，涵盖基于同种异体移植物、合成材料、因子和细胞的技术。
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