College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
Chem Asian J. 2012 Nov;7(11):2527-30. doi: 10.1002/asia.201200512. Epub 2012 Aug 27.
Out of thin air: Catalytic amounts of nickel(II) salt and non-racemic dipyridylphosphine ligand, as well as the stoichiometric hydride source PhSiH(3), formed an effective catalyst system for the Ni(II)-catalyzed asymmetric hydrosilylation of a diverse range of electron-deficient aryl alkyl ketones with enantioselectivities up to 90% ee. The practical potential of the protocol was evinced by its good air-stability.
催化量的镍(II)盐和非外消旋二吡啶基膦配体，以及化学计量的氢化物源 PhSiH(3)，形成了一种有效的催化剂体系，用于 Ni(II)催化的各种缺电子芳基烷基酮的不对称氢化硅烷化反应，对映选择性高达 90%ee。该协议的实际潜力表现为其良好的空气稳定性。
