Ueno A, Tago K
Department of Urology, Yamanashi Medical College, Japan.
Nihon Hinyokika Gakkai Zasshi. 1990 Dec;81(12):1787-99. doi: 10.5980/jpnjurol1989.81.1787.
Protein intake has been shown to raise glomerular filtration rate (GFR). The difference between peak and baseline GFR following acute protein load indicates renal functional reserve (RFR). In this paper, we review 1) normal glomerular function and its regulating factors, 2) the concept of RFR and the mechanism by which the acute protein load induces hyperfiltration response in healthy subjects and 3) the RFR in patients with renal disease.
蛋白质摄入已被证明会提高肾小球滤过率（GFR）。急性蛋白质负荷后峰值GFR与基线GFR之间的差异表明肾功能储备（RFR）。在本文中，我们综述了：1）正常肾小球功能及其调节因素；2）RFR的概念以及急性蛋白质负荷在健康受试者中诱导超滤过反应的机制；3）肾病患者的RFR。
