Radermacher L, Godon J P
Service de Néphrologie, CHU Sart Tilman, Liège.
Acta Clin Belg. 1992;47(5):338-50. doi: 10.1080/17843286.1992.11718252.
The concept of renal functional reserve (RFR) was introduced in the 80's. The renal functional reserve was defined as the ability of the kidney to increase Renal Plasma Flow (RPF) and Glomerular Filtration Rate (GFR) after a stimulus as a protein load. The absence of RFR defines a state of hyperfiltration which seems to be a detrimental factor for the progression of renal failure. The measure of RFR by a protein load test is thus a mean to detect glomerular hyperfiltration and allows to give adequate diet prescription.
肾功储备（RFR）的概念于20世纪80年代提出。肾功储备被定义为肾脏在受到如蛋白质负荷等刺激后增加肾血浆流量（RPF）和肾小球滤过率（GFR）的能力。肾功储备缺失定义了一种超滤状态，这似乎是肾衰竭进展的一个有害因素。因此，通过蛋白质负荷试验来测量肾功储备是检测肾小球超滤的一种手段，并有助于给出适当的饮食处方。
