Suppr超能文献

幼儿意外中毒:发育阶段能否预测接触和摄入的物质类型?

Unintentional poisoning in young children: does developmental stage predict the type of substance accessed and ingested?

作者信息

Schmertmann M, Williamson A, Black D

机构信息

School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia.

出版信息

Child Care Health Dev. 2014 Jan;40(1):50-9. doi: 10.1111/j.1365-2214.2012.01424.x. Epub 2012 Aug 29.

Abstract

BACKGROUND

When children aged 0-4 years are analysed together as a group for poisoning risk, important differences for smaller age intervals by medicinal and non-medicinal substances are masked. These differences have been attributed to child developmental stages but no studies have been conducted that examine the predictive value of child developmental stage for poisoning by substance type, using 3-month age intervals as a proxy for developmental stage and adjusting for the effect of sex, socio-economic status and remoteness of residence.

METHODS

A population-based dataset of unintentional poisoning hospitalizations in children aged 0-4 years was used to predict the type of substance ingested. Associations between the type of substance and age, sex, socio-economic status and remoteness of residence were measured using multivariate logistic regression.

RESULTS

Children aged 12-17 months had significantly higher odds of experiencing a non-medicinal poisoning while children aged 24-41 months had significantly higher odds of experiencing a medicinal poisoning. Males and children from more disadvantaged and outer regional areas had higher odds of experiencing a non-medicinal poisoning.

CONCLUSIONS

Children aged 0-4 years differ in their stage of development and as a consequence, vary significantly in their ability to access their environment. Our results clearly show that odds of poisoning by medicinal substances compared with non-medicinal substances change as children age. This study provides evidence that child development predicts the type of substance accessed and ingested.

摘要

背景

当将0至4岁的儿童作为一个群体来分析中毒风险时,按药物和非药物物质划分的较小年龄区间的重要差异就会被掩盖。这些差异被归因于儿童的发育阶段,但尚未有研究以3个月的年龄区间作为发育阶段的替代指标,并在调整性别、社会经济地位和居住偏远程度的影响后,考察儿童发育阶段对不同类型物质中毒的预测价值。

方法

使用一个基于人群的0至4岁儿童非故意中毒住院数据集来预测摄入物质的类型。采用多变量逻辑回归来衡量物质类型与年龄、性别、社会经济地位和居住偏远程度之间的关联。

结果

12至17个月大的儿童发生非药物中毒的几率显著更高,而24至41个月大的儿童发生药物中毒的几率显著更高。男性以及来自更贫困和偏远地区的儿童发生非药物中毒的几率更高。

结论

0至4岁的儿童在发育阶段存在差异,因此,他们接触周围环境的能力也有显著差异。我们的结果清楚地表明,随着儿童年龄的增长,药物中毒与非药物中毒的几率会发生变化。这项研究提供了证据,表明儿童发育情况可预测接触和摄入的物质类型。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验