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儿童意外中毒:孟加拉国单中心病例系列研究。

Accidental poisoning in children: a single centre case series study in Bangladesh.

机构信息

Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh.

Dhaka Medical College, Dhaka, Bangladesh.

出版信息

BMJ Paediatr Open. 2022 Jul;6(1). doi: 10.1136/bmjpo-2022-001541. Epub 2022 Jul 20.

Abstract

BACKGROUND

Accidental poisoning is a leading cause of unintentional injuries among children in low-income and middle-income countries (LMICs). The overall aspect of this unintentional poisoning is poorly understood in Bangladesh. The objectives of this study were (1) to explore the socio-demographic factors and circumstantial context of accidental poisoning and (2) the prevalence of the type of substances causing it.

METHODS

A descriptive case series study was conducted from April 2019 to February 2020 at a tertiary level hospital of the capital city Dhaka in Bangladesh. Children under 10 years of age admitted to the hospital with accidental poisoning were enrolled in this study. Parents of hospitalised children were interviewed face-to-face using a structured questionnaire. Descriptive statistics were used for data analysis.

RESULTS

A total of 223 children were recruited in this study. Children between 2 and 5 years (60%), men (61%) and children with agility (65.5%) were among the prevalent victims. The majority of cases occurred (65%) in a nuclear family setting. Most mothers (85%) of these children were non-working and most incidents took place in parents' homes (~82%). Nearly 70% of the poisoning incidents took place in the presence of parents and over half of these occurred in the bedroom. Kerosene was the prevalent cause (33%) of accidental poisoning while insecticide/pesticide ranked second (26.5%) followed by medicines (17%) and household chemicals (12). In one-third (31.4%) of the cases, poisoning chemicals were stored in soft drink bottles while two-thirds (67.3%) of the cases were kept in containers other than original ones. Although over 80 parents somewhat knew that chemicals could be harmful to the children if ingested, most of them did not take the safety measures.

CONCLUSION

In this present study we found that preschool-aged children were more victims of accidental poisoning mostly by ingesting kerosene and a majority of the incidents took place in the bedroom while parents were present at home. Our study findings would serve as a baseline for designing future intervention studies and policies.

摘要

背景

意外伤害是低收入和中等收入国家(LMICs)儿童非故意伤害的主要原因。在孟加拉国,人们对这种意外伤害的总体情况了解甚少。本研究的目的是(1)探讨意外中毒的社会人口学因素和环境背景,(2)引起中毒的物质类型的流行情况。

方法

本研究为 2019 年 4 月至 2020 年 2 月在孟加拉国首都达卡的一家三级医院进行的描述性病例系列研究。入组研究的是因意外中毒而住院的 10 岁以下儿童。通过面对面访谈,使用结构化问卷收集住院患儿家长的信息。采用描述性统计方法进行数据分析。

结果

本研究共纳入 223 例患儿。2 至 5 岁儿童(60%)、男孩(61%)和动作敏捷的儿童(65.5%)是常见的受害者。大多数病例(65%)发生在核心家庭中。这些孩子的母亲(85%)大多不工作,大多数事件发生在父母家中(约 82%)。近 70%的中毒事件发生在父母在场的情况下,其中一半以上发生在卧室。煤油是导致意外中毒的主要原因(33%),其次是杀虫剂/农药(26.5%)、药物(17%)和家用化学品(12%)。在三分之一(31.4%)的病例中,中毒化学品储存在软饮料瓶中,而三分之二(67.3%)的病例则储存在非原始容器中。尽管超过 80%的家长知道如果儿童摄入化学物质可能会对他们造成伤害,但大多数家长并未采取安全措施。

结论

在本研究中,我们发现学龄前儿童是意外中毒的主要受害者,大多数是通过摄入煤油,大多数事件发生在父母在家的卧室。我们的研究结果将为设计未来的干预研究和政策提供基线。

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