Lloyd I J
Department of Chemical Pathology, Old Medical School, University of Leeds, UK.
Med Hypotheses. 1990 Nov;33(3):197-9. doi: 10.1016/0306-9877(90)90176-f.
This hypothesis questions the validity of Starling's hypothesis regarding the distribution of water and electrolytes between the intravascular and interstitial compartments. It emphasises the potential importance of the gel state of the extracellular matrix in determining interstitial compliance and the distribution of water and electrolytes between the intravascular and interstitial compartments. Because the physicochemical properties of the extracellular matrix can change rapidly in response to numerous stimuli, it is suggested that the extracellular matrix is an integral and dynamic component of the sodium homeostatic system.
这一假说对斯塔林关于血管内和组织间隙之间水和电解质分布的假说的有效性提出了质疑。它强调了细胞外基质的凝胶状态在决定组织间隙顺应性以及血管内和组织间隙之间水和电解质分布方面的潜在重要性。由于细胞外基质的物理化学性质可因众多刺激而迅速改变，因此有人提出细胞外基质是钠稳态系统不可或缺的动态组成部分。
