Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Am J Perinatol. 2013 Mar;30(3):185-90. doi: 10.1055/s-0032-1322517. Epub 2012 Aug 28.
To determine if tobacco use increases the incidence of preterm premature rupture of the membranes (pPROM) or alters perinatal outcomes after pPROM.
This is a secondary analysis of the databases of three completed Eunice Kennedy Shriver National Institute of Child Health and Human Development-supported Maternal Fetal Medicine Units Network studies. Self-reported tobacco exposure data was obtained. Its relationship with the incidence of pPROM and associated neonatal outcome measures were assessed.
There was no difference in the incidence of pPROM when comparing nonsmokers to those using tobacco. Although a trend was seen between the incidence of pPROM and the amount smoked, this did not reach statistical significance. Among the patients with pPROM, the use of tobacco was not associated with an increase in perinatal morbidity.
Our data do not support a significant relationship between tobacco use and pPROM.
确定吸烟是否会增加胎膜早破（pPROM）的发生率，或改变胎膜早破后的围产结局。
这是对三个已完成的 Eunice Kennedy Shriver 国家儿童健康与人类发育研究所支持的母胎医学单位网络研究数据库的二次分析。获得了自我报告的烟草暴露数据。评估了它与 pPROM 的发生率和相关新生儿结局指标的关系。
比较不吸烟者和吸烟者，pPROM 的发生率没有差异。尽管 pPROM 的发生率与吸烟量之间存在趋势，但未达到统计学意义。在患有 pPROM 的患者中，使用烟草与围产发病率的增加无关。
我们的数据不支持吸烟与 pPROM 之间存在显著关系。
