中国江苏省艾滋病病毒/艾滋病患者群体中六种支原体科物种的流行情况。

The prevalence of six species of Mycoplasmataceae in an HIV/AIDS population in Jiangsu Province, China.

作者信息

Wang B, Wu J-R, Guo H-J, Yang H-T, Ai J, Hui M, Chan C-Y

机构信息

School of Public Health, Southeast University, Nanjing, Jiangsu 210009, People’s Republic of China.

出版信息

Int J STD AIDS. 2012 Aug;23(8):e7-10. doi: 10.1258/ijsa.2009.009396.

DOI:10.1258/ijsa.2009.009396

PMID:22930310

Abstract

This study employed culture and polymerase chain reaction (PCR) to examine the prevalence of Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma fermentans, Mycoplasma penetrans and Mycoplasma pirum in 210 HIV/AIDS patients, 455 sexually transmitted infection (STI) clinic attendees and 245 healthy volunteers from first-void urine specimens for men and endocervical swabs for women. U. urealyticum and M. hominis were detected in 107 (51.0%) and 69 (32.9%) patients in the HIV/AIDS group. At least one of the other four organisms was detected in 34 (16.2%) HIV/AIDS patients, 29 (6.4%) STI clinic attendees and six (2.5%) healthy volunteers. This study showed that U. urealyticum, M. hominis and M. fermentans were significantly more prevalent in HIV/AIDS patients, as were other mycoplasmas. Our results suggest a possible role for co-infection.

摘要

本研究采用培养和聚合酶链反应（PCR）方法，对210例艾滋病毒/艾滋病患者、455例性传播感染（STI）门诊就诊者以及245名健康志愿者的初段尿标本（男性）和宫颈拭子标本（女性）进行检测，以了解解脲脲原体、人型支原体、生殖支原体、发酵支原体、穿透支原体和梨支原体的感染率。艾滋病毒/艾滋病组中，107例（51.0%）患者检测出解脲脲原体，69例（32.9%）患者检测出人型支原体。34例（16.2%）艾滋病毒/艾滋病患者、29例（6.4%）性传播感染门诊就诊者以及6例（2.5%）健康志愿者检测出至少一种其他四种支原体。本研究表明，解脲脲原体、人型支原体和发酵支原体在艾滋病毒/艾滋病患者中的感染率显著更高，其他支原体也是如此。我们的结果提示合并感染可能起作用。