Paula C R, Sampaio M C, Birman E G, Siqueira A M
Department of Microbiology, USP.
Mycopathologia. 1990 Nov;112(2):119-24. doi: 10.1007/BF00436507.
The yeasts of patients with oral cancer has been studied before and during Xr-therapy. Gram and PAS smears revealed an increase of yeast-like structures, during treatment, from 56% to 66% of the cases. Before radiotherapy oral yeasts were isolated from 56% of the patients with cancer represented by Candida albicans (30%); C. tropicalis (12%); C. glabrata and C. krusei (4%), besides six other different species (2%). During radiotherapy yeasts were isolated in 72% of the cases, as follow: C. albicans (36%); C. tropicalis (16%); Rhodotorula rubra (6%); C. kefyr; C. krusei and Pichia farinosa (4%), besides other nine species (2%). C. albicans serotype A represented 93% of the isolated samples, before treatment and 88.8% during Xr-therapy.
口腔癌患者的酵母菌已在放疗前和放疗期间进行了研究。革兰氏染色和PAS涂片显示,在治疗期间,酵母样结构的病例比例从56%增加到66%。放疗前,56%的癌症患者口腔中分离出酵母菌,其中白色念珠菌占30%;热带念珠菌占12%;光滑念珠菌和克柔念珠菌占4%,此外还有其他六种不同菌种占2%。放疗期间,72%的病例分离出酵母菌,具体如下:白色念珠菌占36%;热带念珠菌占16%;深红酵母占6%;凯菲念珠菌、克柔念珠菌和粉状毕赤酵母占4%,此外还有其他九种菌种占2%。白色念珠菌A型血清型在治疗前占分离样本的93%,在放疗期间占88.8%。