Bodey G P
Am J Med. 1984 Oct 30;77(4D):13-9.
Disseminated candidiasis is likely to become an increasing problem in cancer patients. It has occurred in patients undergoing intensive chemotherapy, thermotherapy, and bone marrow transplant. The availability of broad-spectrum cephalosporins with biliary excretion is likely to increase the problem. Although localized candidiasis responds to both topical and parenteral therapy, systemic candidiasis is often fatal, especially in neutropenic patients. A major obstacle to control of this infection is inadequate diagnostic techniques. It is to be hoped that continuing research will yield more effective diagnostic and therapeutic measures.
播散性念珠菌病在癌症患者中可能会成为一个日益严重的问题。它已发生在接受强化化疗、热疗和骨髓移植的患者身上。具有胆汁排泄功能的广谱头孢菌素的使用可能会加剧这一问题。尽管局部念珠菌病对局部和全身治疗均有反应,但系统性念珠菌病往往是致命的,尤其是在中性粒细胞减少的患者中。控制这种感染的一个主要障碍是诊断技术不足。希望持续的研究能产生更有效的诊断和治疗措施。