Sarkar Diptendra K, Lahiri Somdatta, Pandey Sushil
Indian J Surg Oncol. 2010 Jan;1(1):37-9. doi: 10.1007/s13193-010-0009-7. Epub 2010 Aug 7.
To assess the validity of estrogen receptor (ER) status of breast tumor as a prognostic marker in clinical practice in the Indian perspective.
Sixty-three patients of breast cancer attending breast clinic IPGMER, Kolkata were included in this study. All patients underwent surgery. Metastatic status and tumor were done. Immunohistochemistry was also used for further analysis.
Statistically we have proved that advancing course of the disease, there is a tendency of the tumors to become hormone insensitive.
ER has a strong prognostic importance in early breast cancer and can play a major role in optimizing treatment modalities in node negative early breast cancer.
从印度的角度评估乳腺肿瘤雌激素受体（ER）状态作为临床实践中预后标志物的有效性。
本研究纳入了63名在加尔各答IPGMER乳腺诊所就诊的乳腺癌患者。所有患者均接受了手术。进行了转移状态和肿瘤相关检查。还采用免疫组织化学进行进一步分析。
从统计学上我们证明，随着疾病进程的推进，肿瘤有对激素不敏感的趋势。
ER在早期乳腺癌中具有重要的预后意义，并且在优化淋巴结阴性早期乳腺癌的治疗方式方面可发挥主要作用。
