ROLL乳腺肿块切除术的长期预后。
Long-term outcomes after ROLL lumpectomy.
作者信息
Ramesh H S J, Anguille S, Poonawala S, Harris O, Desmond S, Thind R, Chagla L S, Audisio R A
出版信息
Indian J Surg Oncol. 2010 Jan;1(1):47-51. doi: 10.1007/s13193-010-0011-0. Epub 2010 Aug 7.
BACKGROUND
Occult breast lesions are being successfully targeted by means of Radioactive-guided Occult Lesion Localization (ROLL). Several reports demonstrate suitability of ROLL technique to excise non-palpable breast lesions with immediate advantages.
AIM
Evaluation of long-term outcomes after ROLL guided lumpectomy for early breast cancer. MATERIALS AND METHODS A CONSECUTIVE SERIES OF NON PALPABLE EARLY INVASIVE BREAST CANCERS EXCISED WITH ROLL (151 PTS; DECEMBER 2002#ENTITYSTARTX02013;JUNE 2006) WERE FOLLOWED UP FOR LONG-TERM OUTCOMES, I.E. LOCAL AND/OR SYSTEMIC RECURRENCE. OUR FOLLOW-UP PROTOCOL INCLUDED 6 MONTHLY PHYSICIAN ADMINISTERED CLINICAL EXAMINATIONS AND 18 MONTHLY IMAGING, I.E. MAMMOGRAM. BONE SCAN, LIVER AND BRAIN IMAGING WERE REQUESTED ON CLINICAL NEED. CLINICAL AND/OR RADIOLOGICAL SUSPICIOUS LESIONS FOR LOCAL RECURRENCE WERE CONFIRMED PATHOLOGICALLY:
RESULTS
The median follow-up was 46 months with all patients having a minimum 22 months follow-up. 3/151 local recurrences occurred (1.98%).
CONCLUSIONS
Long-term outcomes, i.e. local recurrence of invasive breast cancer excised with ROLL guidance compares well with existing localization techniques.
背景
隐匿性乳腺病变可通过放射性引导隐匿性病变定位（ROLL）技术成功靶向。多项报告表明ROLL技术适用于切除不可触及的乳腺病变，具有即时优势。
目的
评估ROLL引导下保乳手术治疗早期乳腺癌的长期疗效。材料与方法 对一系列采用ROLL技术切除的不可触及的早期浸润性乳腺癌患者（151例；2002年12月至2006年6月）进行长期随访，即局部和/或全身复发情况。我们的随访方案包括每6个月由医生进行一次临床检查，每18个月进行一次影像学检查，即乳房X线摄影。根据临床需要进行骨扫描、肝脏和脑部成像。对局部复发的临床和/或放射学可疑病变进行病理确诊。
结果
中位随访时间为46个月，所有患者至少随访22个月。发生3例局部复发（151例中的3例，1.98%）。
结论
ROLL引导下切除浸润性乳腺癌的长期疗效，即局部复发情况，与现有定位技术相比效果良好。
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