Chaukar Devendra A, Deshmukh Anuja D, Dandekar Mitali R
Department of Head and Neck Surgery, Tata Memorial Hospital, Dr. Ernest Borges Road, Mumbai, 400 012 India.
Indian J Surg Oncol. 2010 Apr;1(2):151-62. doi: 10.1007/s13193-010-0029-3. Epub 2010 Nov 21.
Thyroid cancers cover a large spectrum of disease with diametrically opposite prognosis. At one end of the spectrum we have the well differentiated cancers which carry an excellent prognosis, while at the other end there is anaplastic cancer with high mortality rates and dismal prognosis. Management of thyroid cancers still has some controversial issues due to lack of randomized controlled trials. Extent of surgery, extent of neck dissection, role of radioiodine treatment and thyroid stimulating hormone suppression are still debatable. In this review, we highlight these controversial issues and give guidelines for the management and follow up of patients with thyroid cancer.
甲状腺癌涵盖了一系列预后截然不同的疾病。在这个范围的一端是分化良好的癌症,其预后极佳,而在另一端则是未分化癌,死亡率高且预后不佳。由于缺乏随机对照试验,甲状腺癌的治疗仍存在一些有争议的问题。手术范围、颈部清扫范围、放射性碘治疗的作用以及促甲状腺激素抑制仍然存在争议。在本综述中,我们强调这些有争议的问题,并给出甲状腺癌患者管理和随访的指南。